{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T10:53:21Z","timestamp":1784804001656,"version":"3.55.0"},"reference-count":19,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2019,8,30]],"date-time":"2019-08-30T00:00:00Z","timestamp":1567123200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The influence of risk factors on atrial fibrillation (AF) ablation recurrence is increasingly recognized. We present a sub\u2010analysis of the European Society of Cardiology\u2010European Heart Rhythm Association\u2010European Society of Cardiology AF ablation long\u2010term registry on the effect of traditional risk factors for AF on postablation recurrence, reablation, and complications using real\u2010world data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Risk factors for AF were defined as body mass index \u226527\u00a0kg\/m\u00b2, hypertension, chronic obstructive pulmonary disease, diabetes, alcohol \u22652 units\/day, sleep apnea, smoking, no\/occasional sports activity, moderate\/severe mitral or aortic valve disease, any cardiomyopathy, peripheral vascular disease, chronic kidney disease, heart failure, coronary artery disease\/infarction, and previous pacemaker\/defibrillator implant. Patients were divided in two groups with \u22651 or without risk factors. Primary outcomes were arrhythmia recurrence after blanking period, reablation, and adverse events or death. Differences between the groups and the influence of individual risk factors were analyzed using multivariate Cox regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three thousand sixty nine patients were included; 217 patients were without risk factors. Risk factor patients were older (58.4\u00a0vs 54.1 years), more often female (32%\u00a0vs 19.8%) and had more often persistent AF (27.2%\u00a0vs 23.5%). In a multivariate analysis, patients without risk factors had a hazard ratio of 0.70 (95% CI 0.49\u20100.99) for recurrence compared to risk factor patients. The multivariate hazard ratios for reablation or adverse events\/death were not different between the two groups. Hypertension and body mass index were univariate predictors of recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Patients with \u22651 risk factor had a 30% higher risk for arrhythmia recurrence after ablation, but no differences in risk for repeat ablations and adverse events or death.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.13763","type":"journal-article","created":{"date-parts":[[2019,7,29]],"date-time":"2019-07-29T15:14:23Z","timestamp":1564413263000},"page":"1365-1373","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Influence of risk factors in the ESC\u2010EHRA EORP atrial fibrillation ablation long\u2010term registry"],"prefix":"10.1111","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7715-9536","authenticated-orcid":false,"given":"Serge A.","family":"Trines","sequence":"first","affiliation":[{"name":"Heart Lung Centre Leiden University Medical Centre  Leiden Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4646-0865","authenticated-orcid":false,"given":"Giuseppe","family":"Stabile","sequence":"additional","affiliation":[{"name":"Clinica Montevergine, Mercogliano (AV), and Clinica San Michele  Maddaloni (CE) Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0424-6393","authenticated-orcid":false,"given":"Elena","family":"Arbelo","sequence":"additional","affiliation":[{"name":"Arrhythmia Section, Cardiology Department, Hospital Cl\u00ednic Universitat de Barcelona  Barcelona Spain"},{"name":"Institut d'Investigaci\u00f3 August Pi i Sunyer (IDIBAPS)  Barcelona Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Cardiovasculares (CIBERCV)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0323-4956","authenticated-orcid":false,"given":"Nikolaos","family":"Dagres","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology Heart Center Leipzig at the University of Leipzig  Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5662-8302","authenticated-orcid":false,"given":"Josep","family":"Brugada","sequence":"additional","affiliation":[{"name":"Arrhythmia Section, Cardiology Department, Hospital Cl\u00ednic Universitat de Barcelona  Barcelona Spain"},{"name":"Institut d'Investigaci\u00f3 August Pi i Sunyer (IDIBAPS)  Barcelona Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Cardiovasculares (CIBERCV)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1632-6182","authenticated-orcid":false,"given":"Josef","family":"Kautzner","sequence":"additional","affiliation":[{"name":"Institute for Clinical and Experimental Medicine (IKEM)  Praha Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2560-5167","authenticated-orcid":false,"given":"Evgeny","family":"Pokushalov","sequence":"additional","affiliation":[{"name":"E. Meshalkin National medical research center of the Ministry of Health of the Russian Federation  Novosibirsk Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2764-6779","authenticated-orcid":false,"given":"Aldo P.","family":"Maggioni","sequence":"additional","affiliation":[{"name":"ANMCO Research Centre  Florence Italy"},{"name":"EURObservational Research Programme European Society of Cardiology  Sophia\u2010Antipolis Cedex France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile","family":"Laroche","sequence":"additional","affiliation":[{"name":"EURObservational Research Programme European Society of Cardiology  Sophia\u2010Antipolis Cedex France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6311-4270","authenticated-orcid":false,"given":"Matteo","family":"Anselmino","sequence":"additional","affiliation":[{"name":"Division of Cardiology, \u201cCitt\u00e0 della Salute e della Scienza di Torino\u201d Hospital, Department of Medical Sciences University of Turin  Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9268-4766","authenticated-orcid":false,"given":"Roy","family":"Beinart","sequence":"additional","affiliation":[{"name":"Davidai Arrhythmia Center, Leviev Heart Center, Sheba Medical Center Ramat Gan, Tel Hashomer, and Sackler School of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9523-6416","authenticated-orcid":false,"given":"Vassil","family":"Traykov","sequence":"additional","affiliation":[{"name":"Acibadem City Clinic Tokuda Hospital 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