{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T04:41:41Z","timestamp":1771994501837,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2019,9,5]],"date-time":"2019-09-05T00:00:00Z","timestamp":1567641600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>A common complication of transcatheter aortic valve repair (TAVR) is development of conduction defects requiring pacemaker (PPM) implantation. These defects are not universally permanent.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine the incidence and predictors of persistent device dependency in patients with PPM implantation following TAVR with a self\u2010expanding prosthesis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Records of patients who underwent post\u2010TAVR PPM implantation were reviewed. Patients with persistent complete AV block (AVBIII) one month post\u2010TAVR were compared to those regaining conduction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Between September 2014 and March 2017, 485 patients underwent TAVR with a self\u2010expanding prosthesis; 77 (15.9%) underwent PPM implantation for AVBIII. Device interrogation at one month was available for 61 patients (79%): 22 (36.1%) had resolution of AVBIII while 39 (63.9%) remained pacemaker\u2010dependent. Pre\u2010TAVR right bundle branch block was more frequent in device\u2010dependent patients (19 of 38, 50% vs 4 of 22, 18%; RR 2.75; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.01). Device\u2010dependence was associated with AVBIII as the first postprocedural rhythm (37 of 39, 95% vs 12 of 22, 55%; RR 1.74; <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.0001), earlier implantation (median 1d, IQR: 0\u20101.5d vs 2d, IQR: 1.0\u20104.0d, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.0004), and a shorter duration of hospitalization (median 3d, IQR: 2\u20103.5d vs 4d, IQR: 2\u20105.75d, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.03). Pacemaker dependence was also associated with a higher prosthesis\u2010to left ventricular outflow tract (LVOT) diameter (1.45 \u00b1 0.11\u00a0vs 1.39 \u00b1 0.07; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.02) and the lack of prior aortic valvuloplasty (5 of 39, 13%\u00a0vs 8 of 22, 36%; RR 0.35; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.03).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In patients receiving a PPM following self\u2010expanding TAVR, a long\u2010term pacing requirement can be predicted from the timing of AV block, existing conduction\u2010system disease, larger prosthesis\u2010to\u2010LVOT diameter, and the lack of aortic valvuloplasty.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.13789","type":"journal-article","created":{"date-parts":[[2019,8,20]],"date-time":"2019-08-20T12:57:07Z","timestamp":1566305827000},"page":"1347-1354","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Factors predicting persistence of AV nodal block in post\u2010TAVR patients following permanent pacemaker implantation"],"prefix":"10.1111","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3776-486X","authenticated-orcid":false,"given":"Joshua M.","family":"Lader","sequence":"first","affiliation":[{"name":"Departments of Medicine New York University School of Medicine  New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3479-936X","authenticated-orcid":false,"given":"Chirag R.","family":"Barbhaiya","sequence":"additional","affiliation":[{"name":"Cardiothoracic Surgery New York University School of Medicine  New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kishore","family":"Subnani","sequence":"additional","affiliation":[{"name":"Departments of Medicine New York University School of Medicine  New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Park","sequence":"additional","affiliation":[{"name":"Departments of Medicine New York University School of Medicine  New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony","family":"Aizer","sequence":"additional","affiliation":[{"name":"Departments of Medicine New York University School of Medicine  New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas","family":"Holmes","sequence":"additional","affiliation":[{"name":"Departments of Medicine New York University School of Medicine  New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cezar","family":"Staniloae","sequence":"additional","affiliation":[{"name":"Departments of Medicine New York University School of Medicine  New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathew R.","family":"Williams","sequence":"additional","affiliation":[{"name":"Cardiothoracic Surgery New York University School of Medicine  New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larry A.","family":"Chinitz","sequence":"additional","affiliation":[{"name":"Departments of Medicine New York University School of Medicine  New York New 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