{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T15:15:14Z","timestamp":1748358914924,"version":"3.40.5"},"reference-count":25,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2019,9,3]],"date-time":"2019-09-03T00:00:00Z","timestamp":1567468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Cardiac resynchronization therapy (CRT) is recommended for patients with advanced chronic heart failure. Systolic aortic root motion (SARM) has been investigated in dilated cardiomyopathy patients and found that heart failure patients had reduced SARM. We aimed to investigate the relationship between SARM and response to CRT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifty\u2010six patients with advanced heart failure, wide QRS complex, and LVEF \u226435% were included. Transthoracic echocardiography was performed before, and repeated at 6 months in follow\u2010up. Systolic aortic root motion was measured in each patient before the device implantation. Echocardiographic response to CRT was defined by a \u226515% reduction in left ventricular end\u2010systolic volume at 6 months follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty patients (71%) had CRT response after 6 months of follow\u2010up. In multivariate analysis, significant associates of response to CRT was evaluated adjusting for functional capacity, etiology of cardiomyopathy, QRS duration, baseline left ventricular dimensions\/volumes and SARM. SARM was the only predictor of response to CRT (OR 1.818, 95% CI, 1.101\u20103.003, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.019).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>SARM predicts non\u2010response to CRT and may help in the selection of CRT candidates.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.13792","type":"journal-article","created":{"date-parts":[[2019,8,27]],"date-time":"2019-08-27T10:20:13Z","timestamp":1566901213000},"page":"1471-1476","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Systolic aortic root motion predicts response to cardiac resynchronization therapy"],"prefix":"10.1111","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4957-7102","authenticated-orcid":false,"given":"Umut","family":"Celikyurt","sequence":"first","affiliation":[{"name":"Department of Cardiology Kocaeli University Medical Faculty  Kocaeli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3217-5000","authenticated-orcid":false,"given":"Burak","family":"Acar","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kocaeli University Medical Faculty  Kocaeli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siho","family":"Hidayet","sequence":"additional","affiliation":[{"name":"Department of Cardiology \u0130n\u00f6n\u00fc University Medical Faculty  Malatya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0130rem","family":"Karauzum","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kocaeli University Medical Faculty  Kocaeli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kurtulus","family":"Karauzum","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kocaeli University Medical Faculty  Kocaeli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"Vural","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kocaeli University Medical Faculty  Kocaeli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aysen","family":"Agacdiken","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kocaeli University Medical Faculty  Kocaeli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,9,3]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000096580.26969.9A"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.793273"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurjhf\/hfs055"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.04.024"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2017.05.058"},{"key":"e_1_2_5_7_1","article-title":"Shorter time to begin of QRS fragmentation predicts non\u2010response to cardiac resynchronization therapy in non\u2010ischemic heart failure patients","author":"Celikyurt U","year":"2019","journal-title":"Rev Clin Esp"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.743120"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1510\/icvts.2007.166835"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000112569.27151.F7"},{"key":"e_1_2_5_11_1","first-page":"591","article-title":"Aortic root motion: A marker of left ventricular diastolic dysfunction using M\u2010mode echocardiography? 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