{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:51:14Z","timestamp":1747187474781,"version":"3.40.5"},"reference-count":11,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2019,11,17]],"date-time":"2019-11-17T00:00:00Z","timestamp":1573948800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The aim of the present study is to evaluate whether catheter\u2010induced premature ventricular complexes (PVCs) produced at the presumptive ablation site may aid in the identification of the optimal timing of the earliest local activation for the successful ablation of clinical PVCs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Sixty\u2010three consecutive patients (35 males, age: 53.5 \u00b1 14.4 years) without any exclusion criteria who had undergone PVC ablation between 1 July 2018 and 1 July 2019 constituted our study population. The time interval between the beginning of the EGM and the beginning of the QRS of each catheter\u2010induced PVC (Cath EGM\u2010ECG) and the time interval between the beginning of the EGM of clinical PVCs at the earliest site and the beginning of the QRS of clinical PVCs (PVC earliest EGM\u2010ECG) were noted for each patient. The value of Cath EGM\u2010ECG as a reference for procedural success of ablation was evaluated by examining the relationship between Cath EGM\u2010ECG and PVC earliest EGM\u2010ECG.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty\u2010two patients had successful ablation, and 43 of them (82.7%) had PVC earliest EGM\u2010ECG values greater than or equal to Cath EGM\u2010ECG. Eleven patients had procedural failure, and all of them had PVC earliest EGM\u2010ECG values lower than Cath EGM\u2010ECG. A PVC earliest EGM\u2010ECG value \u20131.5\u00a0ms greater than Cath EGM\u2010ECG predicted successful ablation with a sensitivity of 90.4% and a specificity of 100.0% in the general patient population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Cath EGM\u2010ECG seems to serve as a reliable guide for finding the optimal timing of the earliest site for successful PVC ablation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.13833","type":"journal-article","created":{"date-parts":[[2019,11,7]],"date-time":"2019-11-07T06:24:50Z","timestamp":1573107890000},"page":"1573-1578","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Catheter\u2010induced premature ventricular complexes (PVCs) may aid in the determination of optimal timing for clinical PVC ablation"],"prefix":"10.1111","volume":"42","author":[{"given":"Serdar","family":"Demir","sequence":"first","affiliation":[{"name":"Department of Cardiology University of Health Sciences, Kartal Kosuyolu Training and Research Hospital  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taylan","family":"Akgun","sequence":"additional","affiliation":[{"name":"Department of Cardiology University of Health Sciences, Kartal Kosuyolu Training and Research Hospital  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1103-0013","authenticated-orcid":false,"given":"Kamil","family":"Gulsen","sequence":"additional","affiliation":[{"name":"Department of Cardiology University of Health Sciences, Kartal Kosuyolu Training and Research Hospital  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayhan","family":"Kup","sequence":"additional","affiliation":[{"name":"Department of Cardiology University of Health Sciences, Kartal Kosuyolu Training and Research Hospital  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3022-2734","authenticated-orcid":false,"given":"Abdulkadir","family":"Uslu","sequence":"additional","affiliation":[{"name":"Department of Cardiology University of Health Sciences, Kartal Kosuyolu Training and Research Hospital  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fethullah","family":"Kayan","sequence":"additional","affiliation":[{"name":"Cardiology Clinic Mardin State Hospital  Mardin Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3868-3268","authenticated-orcid":false,"given":"Alper","family":"Kepez","sequence":"additional","affiliation":[{"name":"Department of Cardiology Marmara University School of Medicine  Istanbul 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