{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T16:43:42Z","timestamp":1790959422785,"version":"4.1.0"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,12,3]],"date-time":"2019-12-03T00:00:00Z","timestamp":1575331200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Strict criteria of typical left bundle branch block (LBBB) can help with the prediction for cardiac resynchronization therapy response. The aim of this study is to determine whether the use of strict criteria for both LBBB and right bundle branch block (RBBB) predicts successful QRS correction (\u2264130\u00a0ms) by left bundle branch area pacing (LBBAP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Consecutive patients with pacemaker indications according to the present guideline who also underwent LBBAP implantation were retrospectively assessed. Inclusion criteria were patients with BBB and the baseline QRSd\u00a0&gt;\u00a0130\u00a0ms. Baseline characteristics and pacing parameters were compared between typical and atypical BBB groups. Multivariate logistic regression was used to adjust for covariates that were found in univariate analyses for successful QRS correction by LBBAP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seventy\u2010three patients were enrolled. Among them, 10 (13.6%) had atypical BBB (5 LBBB and 5 RBBB) and 63 (86.4%) had typical BBB (30 LBBB and 33 RBBB). The rate of successful QRS correction was higher in typical\u2010BBB patients (52\/63; 82.5%) than that in atypical\u2010BBB patients (3\/10; 30%), <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001. Paced QRSd was obviously narrower in patients with typical BBB than that in patients with atypical\u2010BBB (118 \u00b1 14\u00a0vs 133 \u00b1 14\u00a0ms, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.003). In multivariate logistic regression, only typical BBB morphology and the implantation depth of 3830 pacing electrode in the ventricular septum were independent predictors for successful QRS correction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study demonstrates that patients with typical\u2010BBB morphology benefit more from LBBAP for QRS correction. Typical BBB morphology together with deep penetration of 3830 ventricular electrode in the interventricular septum predicts the success of QRS correction by LBBAP.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.13849","type":"journal-article","created":{"date-parts":[[2019,11,27]],"date-time":"2019-11-27T06:14:57Z","timestamp":1574835297000},"page":"110-117","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Typical BBB morphology and implantation depth of 3830 electrode predict QRS correction by left bundle branch area pacing"],"prefix":"10.1111","volume":"43","author":[{"given":"Zhixin","family":"Jiang","sequence":"first","affiliation":[{"name":"Department of Cardiology The First Affiliated Hospital of Nanjing Medical University Jiangsu Province Hospital  China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qin","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Cardiology 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