{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T02:05:38Z","timestamp":1762999538816,"version":"3.40.5"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,12,23]],"date-time":"2019-12-23T00:00:00Z","timestamp":1577059200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The outcomes of pulmonary vein isolation (PVI) for persistent atrial fibrillation (AF) are suboptimal. The entire pulmonary venous component (PV\u2010Comp), consisting of the pulmonary veins, their antra, and the area between the antra, provides triggers and substrate for AF. PV\u2010Comp isolation is an alternative strategy for persistent AF ablation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Among 328 patients with persistent AF who underwent a first radiofrequency ablation procedure, 200 patients (PVI, <jats:italic>n<\/jats:italic>\u00a0=\u00a0100; PV\u2010Comp isolation, <jats:italic>n<\/jats:italic>\u00a0=\u00a0100) were selected by propensity score matching. Both groups were followed up for 1 year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At 6\u2010 and 12\u2010month follow\u2010up, atrial tachyarrhythmia (AF\/atrial tachycardia) recurred in 41 and 61 patients in PVI group and 22 (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.006) and 33 patients (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001) in PV\u2010Comp isolation group, respectively. PV\u2010Comp isolation was associated with longer mean time to recurrence (PVI: 8 months, PV\u2010Comp isolation: 10 months, log\u2010rank <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001) and a lower probability of recurrence (odds ratio [OR]\u00a0=\u00a00.32; 95% confidence of interval [CI]\u00a0=\u00a00.18\u20100.56, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001), with no increase in procedural complications (PVI: 5 of 100, PV\u2010Comp isolation: 6 of 100, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.76). Procedure duration was longer in PV\u2010Comp isolation group (PVI: 186 \u00b1 42\u00a0min, PV\u2010Comp isolation: 238 \u00b1 44\u00a0min, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001), as well as fluoroscopy time (PVI: 22 \u00b1 16\u00a0min, PV\u2010Comp isolation: 31 \u00b1 21\u00a0min, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>PV\u2010Comp isolation for persistent AF reduced atrial tachyarrhythmia recurrence up to 1 year compared with PVI alone. While procedure and fluoroscopy time increased, there was no difference in procedural complications.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.13852","type":"journal-article","created":{"date-parts":[[2019,12,6]],"date-time":"2019-12-06T03:26:55Z","timestamp":1575602815000},"page":"68-77","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Isolating the entire pulmonary venous component versus isolating the pulmonary veins for persistent atrial fibrillation: A propensity\u2010matched analysis"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2709-1806","authenticated-orcid":false,"given":"Ahmed I","family":"Elbatran","sequence":"first","affiliation":[{"name":"Cardiology Clinical Academic Group, St. George's University Hospitals NHS Foundation Trust St. George's University of London  London UK"},{"name":"Department of Cardiology Ain Shams University  Cairo Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark M","family":"Gallagher","sequence":"additional","affiliation":[{"name":"Cardiology Clinical Academic Group, St. George's University Hospitals NHS Foundation Trust St. George's University of London  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony","family":"Li","sequence":"additional","affiliation":[{"name":"Cardiology Clinical Academic Group, St. George's University Hospitals NHS Foundation Trust St. George's University of London  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manav","family":"Sohal","sequence":"additional","affiliation":[{"name":"Cardiology Clinical Academic Group, St. George's University Hospitals NHS Foundation Trust St. George's University of London  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abhay","family":"Bajpai","sequence":"additional","affiliation":[{"name":"Cardiology Clinical Academic Group, St. George's University Hospitals NHS Foundation Trust St. George's University of London  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rania","family":"Samir","sequence":"additional","affiliation":[{"name":"Department of Cardiology Ain Shams University  Cairo Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mazen","family":"Tawfik","sequence":"additional","affiliation":[{"name":"Department of Cardiology Ain Shams University  Cairo Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Nabil","sequence":"additional","affiliation":[{"name":"Department of Cardiology Ain Shams University  Cairo Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mervat","family":"Abou\u2010Elmaaty Nabih","sequence":"additional","affiliation":[{"name":"Department of Cardiology Ain Shams University  Cairo Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magdi M","family":"Saba","sequence":"additional","affiliation":[{"name":"Cardiology Clinical Academic Group, St. George's University Hospitals NHS Foundation Trust St. George's University of London  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,12,23]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_8_2_1","DOI":"10.1111\/j.1540-8167.2007.00956.x"},{"doi-asserted-by":"publisher","key":"e_1_2_8_3_1","DOI":"10.1111\/j.1540-8167.1999.tb00211.x"},{"doi-asserted-by":"publisher","key":"e_1_2_8_4_1","DOI":"10.1161\/01.CIR.0000074206.52056.2D"},{"doi-asserted-by":"publisher","key":"e_1_2_8_5_1","DOI":"10.1093\/europace\/euw231"},{"doi-asserted-by":"publisher","key":"e_1_2_8_6_1","DOI":"10.1136\/heart.86.3.265"},{"doi-asserted-by":"publisher","key":"e_1_2_8_7_1","DOI":"10.1016\/j.hrthm.2019.03.012"},{"doi-asserted-by":"publisher","key":"e_1_2_8_8_1","DOI":"10.1016\/j.hrthm.2017.05.012"},{"key":"e_1_2_8_9_1","first-page":"6","article-title":"Complete isolation of the left atrial posterior wall (Box Lesion) to treat longstanding persistent atrial fibrillation","volume":"7","author":"Saad EB","year":"2014","journal-title":"J Atr Fibrillation"},{"doi-asserted-by":"publisher","key":"e_1_2_8_10_1","DOI":"10.1161\/JAHA.116.003885"},{"doi-asserted-by":"publisher","key":"e_1_2_8_11_1","DOI":"10.1016\/j.hrthm.2015.08.019"},{"doi-asserted-by":"publisher","key":"e_1_2_8_12_1","DOI":"10.1007\/s10840-016-0124-7"},{"doi-asserted-by":"publisher","key":"e_1_2_8_13_1","DOI":"10.1161\/CIRCEP.108.797944"},{"doi-asserted-by":"publisher","key":"e_1_2_8_14_1","DOI":"10.1111\/j.1540-8167.2007.00944.x"},{"doi-asserted-by":"publisher","key":"e_1_2_8_15_1","DOI":"10.1111\/j.1540-8159.1994.tb03819.x"},{"doi-asserted-by":"publisher","key":"e_1_2_8_16_1","DOI":"10.1161\/JAHA.116.003894"},{"doi-asserted-by":"publisher","key":"e_1_2_8_17_1","DOI":"10.1056\/NEJMoa1408288"},{"doi-asserted-by":"publisher","key":"e_1_2_8_18_1","DOI":"10.1016\/j.hrthm.2010.01.017"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpace.13852","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.13852","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pace.13852","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.13852","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T20:48:57Z","timestamp":1694119737000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pace.13852"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,23]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["10.1111\/pace.13852"],"URL":"https:\/\/doi.org\/10.1111\/pace.13852","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"type":"print","value":"0147-8389"},{"type":"electronic","value":"1540-8159"}],"subject":[],"published":{"date-parts":[[2019,12,23]]},"assertion":[{"value":"2019-10-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-12-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}