{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T02:48:10Z","timestamp":1784861290992,"version":"3.55.0"},"reference-count":32,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,5,23]],"date-time":"2020-05-23T00:00:00Z","timestamp":1590192000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Patients with existing or anticipated indications for cardiac resynchronisation therapy (CRT), bradycardia, or anti\u2010tachycardia pacing should not be offered subcutaneous defibrillators (SQIDs) but it remains unclear how clinicians should predict future need for these therapies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We applied three SQID selection policies to data collected retrospectively from transvenous implantable cardioverter defibrillator (TV\u2010ICD) implants:<\/jats:p><jats:p>(a) approach A, SQID used in inherited channelopathies and idiopathic ventricular fibrillation only;<\/jats:p><jats:p>(b) approach B, as above, plus all hypertrophic cardiomyopathy and grown\u2010up congenital heart disease patients;<\/jats:p><jats:p>(c) approach C, as above, plus primary and secondary prevention (for ventricular fibrillation only) of SCD in patients with QRS\u00a0&lt;150\u00a0ms. Approach C reflects current ESC and AHA\/ACC\/HRS guidelines.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>338 of 951 patients with TV\u2010ICD were considered for SQID after excluding 613 patients with contraindications. Approaches A, B, and C yielded 45 (4.7%), 89 (9.4%), and 338 (35.5%) patients suitable for SQID, respectively. Use of SQID resulted in more frequent ICD shocks compared to TV\u2010ICD with approach C only (0.43\u00a0vs 0.23 per 1000 patient\u2010days; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.03). Rates of CRT upgrade were comparable across selection criteria (0, 0.03, and 0.07 per 1000 patient\u2010days for approaches A, B, and C, respectively; <jats:italic>P<\/jats:italic>\u00a0=\u00a0NS). Risk of early mortality was higher when more liberal inclusion criteria were used (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.003).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>One in three patients receiving ICDs may be suitable for SQID under current ESC and AHA\/ACC\/HRS guidelines. This proportion is influenced significantly by the selection criteria used, and the criteria used by a physician should be informed by the estimated survival of the patient, risk of shocks for MVT, future pacing, and CRT requirements.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.13936","type":"journal-article","created":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T05:35:52Z","timestamp":1589002552000},"page":"558-565","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Impact of different selection policies on subcutaneous ICD implants and therapies"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9577-4476","authenticated-orcid":false,"given":"Idris","family":"Harding","sequence":"first","affiliation":[{"name":"Department of Cardiology King's College Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6962-3199","authenticated-orcid":false,"given":"Amit","family":"Kaura","sequence":"additional","affiliation":[{"name":"Department of Cardiology Imperial College  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur","family":"Yue","sequence":"additional","affiliation":[{"name":"Department of Cardiology Southampton General Hospital  Southampton Hampshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Roberts","sequence":"additional","affiliation":[{"name":"Department of Cardiology Southampton General Hospital  Southampton Hampshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis","family":"Murgatroyd","sequence":"additional","affiliation":[{"name":"Department of Cardiology King's College Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul A","family":"Scott","sequence":"additional","affiliation":[{"name":"Department of Cardiology King's College Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,5,23]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa013474"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199612263352601"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa043399"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199711273372202"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2003.02305.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0909545"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.111.964676"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehv316"},{"key":"e_1_2_8_10_1","first-page":"e272","article-title":"2017 AHA\/ACC\/HRS guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society","volume":"138","author":"Al\u2010Khatib SM","year":"2018","journal-title":"Circulation"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-017-0243-9"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2011.03255.x"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000035996.46455.09"},{"key":"e_1_2_8_14_1","unstructured":"National Institute for Health and Care Excellence.Cardiac resynchronisation therapy for the treatment of heart failure. 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