{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:28:19Z","timestamp":1790738899725,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,6,27]],"date-time":"2020-06-27T00:00:00Z","timestamp":1593216000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["Grant Number: 81970284"],"award-info":[{"award-number":["Grant Number: 81970284"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To assess the electrocardiogram patterns of paced QRS narrowing after successful left bundle branch area pacing (LBBAP) and echocardiographic measurements in patients with bradycardia and bundle branch block (BBB).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We prospectively enrolled 55 consecutive bradycardia patients with BBB and left ventricular ejection fraction \u226540% who had attempted LBBAP. Successful LBBAP was defined as paced QRS morphology of a right BBB (RBBB) pattern in lead V1 and a recording of abruptly shortened and then constant stimulus to peak left ventricular activation time with high and low output. Pacing characteristics and echocardiographic measurements were evaluated perioperatively and at 6\u2010month follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The success rate of LBBAP was 83.6% in patients with BBB, and median cumulative X\u2010ray dose\u2010area product was 100.5 \u00b5Gym<jats:sup>2<\/jats:sup> (60.0, 179.3). LBBAP was successful in 19 of 26 patients with left BBB (LBBB) (73.1%) and in 27 of 29 patients with RBBB (93.1%). The QRS duration (QRSd) was significantly shortened in patients with LBBB (QRSd 169.4 \u00b1 22.6 to 119.6 \u00b1 9.5\u00a0ms), and five forms of QRSd narrowing were observed in patients with RBBB with the mean QRSd shortened from 143.1 \u00b1 16.6\u00a0ms to 119.5 \u00b1 11.7\u00a0ms. The thresholds for narrowing of QRSd were higher in RBBB than LBBB (1.74 \u00b1 0.36 V\/0.4\u00a0ms vs 0.79 \u00b1 0.17 V\/0.4\u00a0ms, <jats:italic>P\u00a0<\/jats:italic>&lt;\u00a0.001). During the 6\u2010month follow\u2010up, both left and right ventricular synchronies were improved, and narrow QRSd persisted in patients with BBB.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In most bradycardia patients, RBBB could be completely or partially narrowed by LBBAP at different pacing models in addition to the correction of LBBB with LBBAP.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.13982","type":"journal-article","created":{"date-parts":[[2020,6,11]],"date-time":"2020-06-11T06:34:32Z","timestamp":1591857272000},"page":"781-790","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["ECG patterns of successful permanent left bundle branch area pacing in bradycardia patients with typical bundle branch block"],"prefix":"10.1111","volume":"43","author":[{"given":"Xiaofei","family":"Li","sequence":"first","affiliation":[{"name":"State Key Laboratory of Cardiovascular Disease Cardiac Arrhythmia Center Fuwai Hospital National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2325-3839","authenticated-orcid":false,"given":"Xiaohan","family":"Fan","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Cardiovascular Disease Cardiac Arrhythmia Center Fuwai Hospital National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Echocardiography Fuwai Hospital National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5373-7511","authenticated-orcid":false,"given":"Xiaohui","family":"Ning","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Cardiovascular Disease Cardiac Arrhythmia Center Fuwai Hospital National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erpeng","family":"Liang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Cardiovascular Disease Cardiac Arrhythmia Center Fuwai Hospital National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wentao","family":"Ma","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Cardiovascular Disease Cardiac Arrhythmia Center Fuwai Hospital National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Echocardiography Fuwai Hospital National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhimin","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Cardiovascular Disease Cardiac Arrhythmia Center Fuwai Hospital National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing 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