{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T22:21:49Z","timestamp":1785450109807,"version":"3.56.0"},"reference-count":14,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,8,11]],"date-time":"2020-08-11T00:00:00Z","timestamp":1597104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>Nonsustained ventricular tachycardia (NSVT) occurs frequently in patients with dilated cardiomyopathy (DCM), especially in high\u2010risk patients. The role of rapid\u2010rate NSVT (RR\u2010NSVT) documented by an implantable cardioverter\u2010defibrillator (ICD) in DCM patients has not been fully explored. This study aimed to determine the relationship between RR\u2010NSVT and the occurrence of ventricular tachyarrhythmias (VTAs) in DCM patients with ICD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From December 2000 to December 2017, 136 DCM patients received ICD or cardiac resynchronization therapy defibrillator (CRT\u2010D) implantation for primary or secondary prevention of VTAs. Based on the occurrence of documented RR\u2010NSVT, patients were classified into RR\u2010NSVT (\u2212) or RR\u2010NSVT (+) groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Result<\/jats:title><jats:p>During the median follow\u2010up of 4.5 years, 50.0% (68\/136) patients experienced \u22651 episode, and 25.0% (34\/136) patients experienced \u22653 episodes of RR\u2010NSVT. Event\u2010free survival for VTAs was significantly higher in the RR\u2010NSVT (\u2212) group, whereas those for heart failure admission and cardiovascular mortality were comparable between groups. In the multivariate Cox regression analysis, any RR\u2010NSVT showed a positive association with the occurrence of VTAs (hazard ratio: 5.087; 95% confidence interval: 2.374\u201010.900; <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001). In RR\u2010NSVT (+) patients, a cluster (\u22653 times\/6 months) and frequent pattern (\u22653 runs\/day) of RR\u2010NSVT were observed in 42.6% (29\/68) and 30.9% (21\/68) patients, respectively, who showed further increased incidence of VTAs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In DCM patients with ICD\/CRT\u2010D, 50.0% patients experienced at least one episode of RR\u2010NSVT. RR\u2010NSVT documentation showed a positive association with subsequent occurrence of VTAs, suggesting the importance of constructive arrhythmia management for patients with RR\u2010NSVT.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.14027","type":"journal-article","created":{"date-parts":[[2020,7,31]],"date-time":"2020-07-31T09:44:48Z","timestamp":1596188688000},"page":"1086-1095","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Rapid\u2010rate nonsustained ventricular tachycardias in high\u2010risk dilated cardiomyopathy patients"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0585-6134","authenticated-orcid":false,"given":"Wei\u2010Chieh","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine Hokkaido University Graduate School of Medicine  Sapporo Japan"},{"name":"Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital Chang Gung University College of Medicine  Kaohsiung Taiwan"},{"name":"Institute of Clinical Medicine College of Medicine, National Cheng Kung University  Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaya","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Hokkaido University Graduate School of Medicine  Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisashi","family":"Yokoshiki","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Hokkaido University Graduate School of Medicine  Sapporo Japan"},{"name":"Department of Cardiovascular Medicine Sapporo City General Hospital  Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taro","family":"Temma","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Hokkaido University Graduate School of Medicine  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Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumi","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Hokkaido University Graduate School of Medicine  Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihisa","family":"Anzai","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Hokkaido University Graduate School of Medicine  Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,8,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ehj.2004.03.022"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccep.2016.04.003"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.12.063"},{"key":"e_1_2_8_5_1","first-page":"721","article-title":"Prognostic role of non\u2010sustained ventricular 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