{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T21:38:11Z","timestamp":1772055491349,"version":"3.50.1"},"reference-count":13,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,9,22]],"date-time":"2020-09-22T00:00:00Z","timestamp":1600732800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The discussion about the feasibility of empiric pacemaker implantation in patients with preexisting atrioventricular (AV) conduction disorders continues. The aim of the study was to determine the etiology of syncope and the need for pacemaker insertion in patients with AV conduction impairment using implantable loop recorder (ILR).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>ILR was implanted after negative diagnostic workup in 37 patients with syncope (24 men, 13 women, age 72\u00a0\u00b1\u00a010 years) and preexisting impairment of AV conduction. First\u2010degree AV block (AVB I) was present in 26 patients, and bundle branch block (BBB) in 17 patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>ILR\u2010based diagnosis was made in 28 patients (75%)\u2014sinus arrest in 13 patients, complete AVB in 10 patients, and vasodepressor syncope in five patients. In patients with preexisting BBB, sinus arrest occurred during ILR monitoring significantly more frequently than in patients without BBB (53%\u00a0vs 20%, <jats:italic>P<\/jats:italic> = .03). Complete AVB was significantly less common in patients with preexisting BBB than in patients without BBB (12%\u00a0vs 40%, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.04). On multivariate regression analysis, the only independent predictor of AVB occurrence during ILR monitoring was preexisting AVB I (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.03). The only independent predictor of sinus arrest during ILR monitoring was preexisting BBB (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.03).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In patients with preexisting AV conduction disorders, prevailing syncopal mechanism during ILR monitoring was asystole. However, sinus arrest occurred more often than complete AVB and was predicted by preexisting BBB. Preexisting AVB was\u00a0a predictor of complete AVB during ILR monitoring.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.14064","type":"journal-article","created":{"date-parts":[[2020,9,22]],"date-time":"2020-09-22T13:23:00Z","timestamp":1600780980000},"page":"1268-1272","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Etiology of syncope in patients with preexisting atrioventricular conduction disorders"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7075-9480","authenticated-orcid":false,"given":"Peter","family":"Mitro","sequence":"first","affiliation":[{"name":"Cardiology Clinic Safarik University, VUSCH  Ko\u0161ice Slovakia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milo\u0161","family":"\u0160imurda","sequence":"additional","affiliation":[{"name":"Cardiology Clinic Safarik University, VUSCH  Ko\u0161ice Slovakia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zora","family":"Laz\u00farov\u00e1","sequence":"additional","affiliation":[{"name":"Cardiology Clinic Safarik University, VUSCH  Ko\u0161ice Slovakia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Jakubov\u00e1","sequence":"additional","affiliation":[{"name":"Cardiology Clinic Safarik University, VUSCH  Ko\u0161ice Slovakia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,9,22]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euv425"},{"key":"e_1_2_7_3_1","first-page":"213","article-title":"Syncope and bundle branch block. Diagnostic yield of a stepped use of electrophysiology study and implantable loop recorders","volume":"64","author":"Azocar D","year":"2011","journal-title":"Rev Esp Cardiol"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.12666"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy037"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eut206"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/eupc.2002.0265"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/hc4201.097837"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.112.975102"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.12946"},{"key":"e_1_2_7_11_1","first-page":"100386","article-title":"Role of baseline 12\u2010lead ECG in predicting syncope caused by arrhythmia in patients investigated using an implantable loop recorder","volume":"24","author":"Sandgren E","year":"2019","journal-title":"Int J Cardiol Heart Vasc"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr071"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acvd.2012.12.002"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2014.03.040"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.14064","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pace.14064","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.14064","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T20:50:41Z","timestamp":1693860641000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pace.14064"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,22]]},"references-count":13,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["10.1111\/pace.14064"],"URL":"https:\/\/doi.org\/10.1111\/pace.14064","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"value":"0147-8389","type":"print"},{"value":"1540-8159","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,22]]},"assertion":[{"value":"2020-05-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}