{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T13:53:32Z","timestamp":1791726812182,"version":"4.3.4"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,11,26]],"date-time":"2020-11-26T00:00:00Z","timestamp":1606348800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Air bubble intrusion through transseptal sheaths during left atrial (LA) catheter ablation can cause cerebral embolisms, especially when using complex\u2010shape catheters. This study aimed to compare the incidence of silent cerebral events (SCEs) after atrial fibrillation (AF) catheter ablation using a mini\u2010basket catheter (IntellaMap Orion; Boston Scientific) between the following groups: group SP, strict prevention of LA air intrusion and group CP, conventional air intrusion prevention.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We enrolled 123 consecutive AF patients (group SP, n\u00a0=\u00a061 and group CP, n\u00a0=\u00a062) who underwent brain magnetic resonance imaging after a local\u2010impedance\u2010guided ablation using one mini\u2010basket catheter and one circular mapping catheter. The preventive strategy in group SP included (a) the insertion of the mini\u2010basket catheter into the transseptal sheaths in a container filled with heparinized saline and (b) no exchange of all catheters over the sheaths.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>SCEs were detected in 67 patients (54.5%), and the incidence of SCEs did not significantly differ between groups SP and CP (55.7%\u00a0vs 53.2%; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.780). A multivariate analysis demonstrated that an older age, non\u2010paroxysmal AF, and radiofrequency (RF) power output were independent positive predictors of SCEs (odds ratios: 1.079, 5.613, and 1.405; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.005,\u00a0&lt;.001, and .012). On the follow\u2010up MR imaging, 83.5% of the SCEs in group SP and 87.7% in group CP disappeared (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.398).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Strict prevention of LA air intrusion may have no additional effect for reducing the incidence of SCEs after local impedance\u2010guided AF ablation using a mini\u2010basket catheter. An older age, non\u2010paroxysmal AF, and high\u2010power RF applications may increase the risk of SCEs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.14131","type":"journal-article","created":{"date-parts":[[2020,11,20]],"date-time":"2020-11-20T22:33:57Z","timestamp":1605911637000},"page":"71-81","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effect of preventing air intrusion on silent strokes during atrial fibrillation ablation using a mini\u2010basket catheter"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9777-4592","authenticated-orcid":false,"given":"Kohki","family":"Nakamura","sequence":"first","affiliation":[{"name":"Division of Cardiology Gunma Prefectural Cardiovascular Center  Maebashi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takehito","family":"Sasaki","sequence":"additional","affiliation":[{"name":"Division of Cardiology Gunma 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