{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:58:43Z","timestamp":1761562723388,"version":"3.40.5"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,1,5]],"date-time":"2021-01-05T00:00:00Z","timestamp":1609804800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We sought to assess the safety of a restrictive permanent pacemaker implantation (PPI) strategy after transcatheter aortic valve implantation (TAVI) as compared to a liberal strategy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Conduction disturbances resulting in PPI are common after TAVI. However, conduction disturbances may be transient and PPI may be superfluous in some patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Until August 2015, we performed PPI in all patients with new complete left bundle branch block (LBBB, QRS\u00a0&gt;\u00a0120\u00a0milliseconds) or higher degree atrioventricular (AV) blocks (liberal strategy). From September 2015 onwards, LBBB established an indication for PPI only in the presence of new\u2010onset AV block (PQ\u00a0&gt;\u00a0200\u00a0milliseconds) (restrictive strategy). We analyzed the impact of the restrictive strategy on pacemaker implantation rate, duration of hospital stay, and 1\u2010year mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Between January 2014 and December 2016, 383 consecutive, pacemaker\u2010naive patients underwent TAVI with the liberal PPI strategy and subsequently 384 with the restrictive strategy. The restrictive strategy significantly reduced the percentage of patients undergoing PPI before discharge (17.2%\u00a0vs. 38.1%, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001) and length of hospital stay (intensive care unit 52 \u00b1 55\u00a0vs. 60 \u00b1 52\u00a0hours, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001; general ward 10.6\u00a0\u00b1 5.7\u00a0vs. 11.5 \u00b1 5.7 days, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.001). One\u2010year all\u2010cause mortality was not significantly different between groups (14.1%\u00a0vs. 11.7%, log\u2010rank <jats:italic>p<\/jats:italic>\u00a0=\u00a0.28). However, sudden death was more frequent in the restrictive group (3.4%\u00a0vs. 1.3%, log\u2010rank <jats:italic>p<\/jats:italic>\u00a0=\u00a0.049).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>As compared to a liberal indication for PPI, a restrictive indication reduced PPI rate and length of hospital stay without significantly affecting all\u2010cause mortality. The observed increase in the risk of sudden death with the restrictive PPI indication deserves further investigation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.14156","type":"journal-article","created":{"date-parts":[[2020,12,29]],"date-time":"2020-12-29T13:29:20Z","timestamp":1609248560000},"page":"240-246","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effect of a restrictive pacemaker implantation strategy on mortality after transcatheter aortic valve implantation"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0785-8846","authenticated-orcid":false,"given":"Simon","family":"Schoechlin","sequence":"first","affiliation":[{"name":"Division of Cardiology and Angiology II University Heart Centre Freiburg  Bad Krozingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Minners","sequence":"additional","affiliation":[{"name":"Division of Cardiology and Angiology II University Heart Centre Freiburg  Bad Krozingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Jadidi","sequence":"additional","affiliation":[{"name":"Division of Cardiology and Angiology II University Heart Centre Freiburg  Bad Krozingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fares","family":"Abduljalil","sequence":"additional","affiliation":[{"name":"Division of Cardiology and Angiology II University Heart Centre Freiburg  Bad Krozingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Ruile","sequence":"additional","affiliation":[{"name":"Division of Cardiology and Angiology II University Heart Centre Freiburg  Bad Krozingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franz\u2010Josef","family":"Neumann","sequence":"additional","affiliation":[{"name":"Division of Cardiology and Angiology II University Heart Centre Freiburg  Bad Krozingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Arentz","sequence":"additional","affiliation":[{"name":"Division of Cardiology and Angiology II University Heart Centre Freiburg  Bad Krozingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,1,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1202277"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eut206"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2015.03.054"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2013.08.015"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-014-0791-2"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.07.014"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jjcc.2017.06.007"},{"key":"e_1_2_8_9_1","article-title":"Long\u2010term clinical impact of permanent cardiac pacing after transcatheter aortic valve implantation with the CoreValve prosthesis: a single center experience","author":"L\u00f3pez\u2010Aguilera 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