{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T09:46:55Z","timestamp":1793094415584,"version":"4.5.0"},"reference-count":11,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,2,16]],"date-time":"2021-02-16T00:00:00Z","timestamp":1613433600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Temporary cardiac pacing, conventionally achieved using a passive transvenous pacing wire, can be life\u2010saving for unstable arrhythmias. However, they run the risk of complications, the longer they remain in\u2010situ. Externalized prolonged temporary pacing (EPTP), using active\u2010fixation lead and an externalized pulse generator; may be an alternative for transient pacing indications, concurrent illness or sepsis that precludes permanent pacing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Sixty\u2010seven patients (mean age 69 \u00b1 14 years; 82% male) underwent EPTP between November 2011 and April 2019. EPTP was performed in a sterile facility, under fluoroscopy, using active\u2010fixation leads anchored to the right ventricle septum. Externalized lead was connected to a re\u2010sterilized pulse generator and secured to anterior chest wall with transparent dressings. EPTP indications and patient outcomes were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Pacing indications were high\u2010grade atrio\u2010ventricular (AV) block (73.2%), sinus arrest (14.9%), overdrive suppression of VT (5.9%) and pause\u2010dependent VT (4.5%). Reasons for ETPT rather than permanent pacing included: sepsis (38.8%), CIED\u2010related infection (8.9%), transient pacing indication (25%), to allow further investigations prior to decision on CIED type (22%), and over\u2010drive arrhythmia suppression (6%). Sixty three percent patients were severely ill in an ICU. Mean duration of pacing was 16 \u00b1 12 days. Sixty seven percent patients subsequently received a CIED and had no evidence of device\u2010related infection at 1\u2010year post\u2010implant. There were three non\u2010fatal complications during EPTP while no deaths were attributed to EPTP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>EPTP is a safe and useful method of prolonged temporary pacing for patients who require chronotropic support, but in whom immediate permanent pacemaker implantation is contraindicated.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.14187","type":"journal-article","created":{"date-parts":[[2021,2,6]],"date-time":"2021-02-06T04:15:00Z","timestamp":1612584900000},"page":"506-512","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The indications and safety of prolonged temporary pacing using active\u2010fixation leads and externalized pulse generator"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4488-0041","authenticated-orcid":false,"given":"Nisar H","family":"Shah","sequence":"first","affiliation":[{"name":"Sandwell &amp; West Birmingham NHS Trust  Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parin","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Cardiology University Hospital of Wales  Cardiff UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hossam","family":"Elsayed","sequence":"additional","affiliation":[{"name":"Good Hope Hospital  Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"O'Callaghan","sequence":"additional","affiliation":[{"name":"Department of Cardiology University Hospital of Wales  Cardiff UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fong T","family":"Leong","sequence":"additional","affiliation":[{"name":"Department of Cardiology University Hospital of Wales  Cardiff UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaheer","family":"Yousef","sequence":"additional","affiliation":[{"name":"Department of Cardiology University Hospital of Wales  Cardiff UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,2,16]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"339","article-title":"Complications associated with 64 temporary pacing wires implanted at a district general hospital\u2014should this procedure be reserved for specialist centres?","volume":"9","author":"Brown A","year":"2002","journal-title":"Br J Cardiol"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/pmj.79.934.463"},{"key":"e_1_2_9_4_1","first-page":"11","article-title":"Transvenous pacing\u2014a dying art for a dying heart?","volume":"17","author":"Artis NJ","year":"2010","journal-title":"Br J Cardiol"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.01.006"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eut031"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016925309136722"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12471-019-01307-x"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2018.11.026"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eut045"},{"key":"e_1_2_9_11_1","first-page":"304","article-title":"Outcomes of standard permanent active fixation leads for temporary pacing","volume":"6","author":"Cipriano R","year":"2020","journal-title":"JACC"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.07.041"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.14187","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pace.14187","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.14187","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T11:42:22Z","timestamp":1693654942000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pace.14187"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,16]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1111\/pace.14187"],"URL":"https:\/\/doi.org\/10.1111\/pace.14187","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"value":"0147-8389","type":"print"},{"value":"1540-8159","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,16]]},"assertion":[{"value":"2020-06-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}