{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:21:35Z","timestamp":1790788895759,"version":"4.1.0"},"reference-count":10,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,4,9]],"date-time":"2021-04-09T00:00:00Z","timestamp":1617926400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2021,5]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Computed tomography (CT) has an established role in detecting perforation of implanted pacemaker and defibrillator leads. The clinical significance of incidental finding of delayed lead perforation remains unclear. The aim of this study was to assess the prevalence of lead perforation as detected by CT in a cohort of patients undergoing transvenous laser lead extraction and characterize the association between finding of incidental lead perforation with periprocedural outcomes.<\/jats:p><\/jats:sec>Methods<\/jats:title>Consecutive patients that underwent chest CT and lead extraction were retrospectively assessed for presence of lead perforation. A total of 143 patients and 348 leads were assessed. The finding of lead perforation was correlated with findings from peri\u2010procedural transesophageal echocardiography (TEE) and outcomes of the lead extraction procedure.<\/jats:p><\/jats:sec>Results<\/jats:title>Lead perforations (including perforations\u00a0<5\u00a0mm and \u22655\u00a0mm) were detected in 66 (46%) patients and 73 (21%) leads. Lead perforation \u22655\u00a0mm were less common and detected in 13 (9%) of patients and 14 (4%) of leads. There was no significant difference in the rates of peri\u2010procedural death, cardiac avulsion, cardiac tamponade or post\u2010extraction pericardial effusion in patients with and without lead perforation.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Incidental delayed lead perforations detected by CT are common and do not correlate with significant TEE findings or adverse peri\u2010procedural outcomes in patients undergoing lead extraction. Larger studies are needed to further characterize the frequency and safety of these findings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.14229","type":"journal-article","created":{"date-parts":[[2021,3,31]],"date-time":"2021-03-31T06:45:21Z","timestamp":1617173121000},"page":"936-942","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Clinical significance of incidentally detected lead perforations by computed tomography"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5510-0223","authenticated-orcid":false,"given":"Prerana","family":"Bhatia","sequence":"first","affiliation":[{"name":"Division of Cardiology Department of Medicine University of California San Diego La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommy","family":"Chiou","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Medicine University of California San Diego La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Svennberg","sequence":"additional","affiliation":[{"name":"Department of Medicine Karolinska Institutet\u2013Karolinksa University Hospital Huddinge Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swapnil","family":"Khoche","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology University of California San Diego La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"Jacobs","sequence":"additional","affiliation":[{"name":"Department of Radiology University of California San Diego San Diego California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Travis","family":"Pollema","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery University of California San Diego La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Pretorius","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery University of California San Diego La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0473-1826","authenticated-orcid":false,"given":"Ulrika","family":"Birgersdotter\u2010Green","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Medicine University of California San Diego La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,4,9]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"96","article-title":"Incidence and predictors of clinically relevant cardiac perforation associated with systematic implantation of active\u2010fixation pacing and defibrillation leads: a single\u2010centre experience with over 3800 implanted leads","volume":"19","author":"Cano \u00d3","year":"2017","journal-title":"Europace"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eun363"},{"key":"e_1_2_10_4_1","first-page":"1031","article-title":"Diagnosis and management of iatrogenic cardiac perforation caused by pacemaker and defibrillator leads","volume":"19","author":"Rajkumar 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