{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T17:18:15Z","timestamp":1790875095211,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,4,24]],"date-time":"2021-04-24T00:00:00Z","timestamp":1619222400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Ventricular tachycardia (VT) ablation is a complex procedure that requires remarkable catheter manipulation skill, great mapping accuracy and catheter stability, and can expose patients to serious complications. Magnetic navigation system (RMN)\u2010guided ablation and contact force\u2010sensing (CFS) catheters have the potential to overcome these obstacles. We performed a systematic review and updated meta\u2010analysis of all available studies evaluating the outcomes of VT ablation by using RMN\u2010guided compared to manual navigation (MAN)\u2010guided, with and without CFS catheters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>MEDLINE\/PubMed, Cochrane, and Google Scholar were searched for randomized controlled trials (RCT) or observational studies with multivariate adjustment comparing RMN\u2010guided versus MAN\u2010guided VT ablation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirteen studies enrolling 1348 patients (656 RMN\u2010guided vs. 692 MAN\u2010guided) were included. CFS catheter were used in 14% of MAN\u2010guided patients. In comparison to MAN\u2010guided and CFS\u2010guided, RMN\u2010guided VT ablation was associated with a significant higher acute ablation success (OR 2.32, 1.66\u20133.23 and OR 2.91, 1.29\u20136.53, respectively) but similar results in term of long\u2010term VT recurrence (OR 0.75, 0.56\u20131.01 and OR 0.79, 0.27\u20132.36, respectively). RMN\u2010guided showed a better safety profile (for all complications, OR 0.52, 0.34\u20130.81) and allowed a significant x\u2010ray reduction compared to MAN\u2010guided (OR 0.21, 0.14\u20130.32) and CFS\u2010guided VT ablation (OR 0.23, 0.11\u20130.52, all 95% CI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>RMN\u2010guided was superior to MAN\u2010guided and CFS\u2010guided VT ablation in term of acute ablation success, all complications endpoint, and reduction of fluoroscopy exposure, but did not reduce long\u2010term VT recurrence. Large prospective multicenter randomized trials are needed to confirm these findings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.14231","type":"journal-article","created":{"date-parts":[[2021,4,7]],"date-time":"2021-04-07T04:48:46Z","timestamp":1617770926000},"page":"1102-1114","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Outcomes of manual versus remote magnetic navigation for catheter ablation of ventricular tachycardia: a systematic review and updated meta\u2010analysis"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1542-8646","authenticated-orcid":false,"given":"Alessandro","family":"Blandino","sequence":"first","affiliation":[{"name":"Division of Cardiology Mauriziano Umberto I Hospital  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Bianchi","sequence":"additional","affiliation":[{"name":"Division of Cardiology Mauriziano Umberto I Hospital  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Sibona Masi","sequence":"additional","affiliation":[{"name":"Division of Cardiology Mauriziano Umberto I Hospital  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Mazzanti","sequence":"additional","affiliation":[{"name":"Molecular Cardiology Istituti Clinici Scientifici Maugeri Istituto di Ricovero e Cura a Carattere Scientifico  Pavia Italy"},{"name":"Department of Molecular Medicine University of Pavia  Pavia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizio","family":"D'Ascenzo","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Medical Sciences AOU Citt\u00e0 della Salute e della Scienza University of Turin  Turin 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