{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:06:41Z","timestamp":1787501201725,"version":"build-2736575974"},"reference-count":31,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,6,16]],"date-time":"2021-06-16T00:00:00Z","timestamp":1623801600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the efficacy and safety of His\u2010bundle pacing (HBP) compared with the traditional biventricular pacing (BVP) on patients with brady\u2010arrhythmias, who suffer from permanent atrial fibrillation (AF) and heart failure with reduced ejection fraction (HFrEF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>All patients with brady\u2010arrhythmias, permanent AF and HFrEF were continuously enrolled from January 2017 to July 2019 and followed up for at least 12 months. The differences in QRS duration (QRSd), New York Heart Association (NYHA) classification, left ventricular ejection fraction (LVEF), tricuspid regurgitation grade, mitral regurgitation grade, left ventricular end\u2010diastolic diameter (LVEDD), and left atrial size were compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 52 patients were enrolled: 37 patients were with HBP and 15 patients with BVP. There was no electrode dislodged, perforation, infection or thrombosis during the follow\u2010up of 18.12\u2009\u00b1\u20094.45 months. The success rate for HBP implantation was 88.10%. The capture threshold of his\u2010bundle and the threshold of the left ventricular lead remained stable during follow\u2010up. LVEF increased to higher than 50% in 11 patients with HBP (29.73%). The NYHA classification (both\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      &lt;\u00a0.001), LVEF (both\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      &lt;\u00a0.001) and LVEDD improved significantly during the follow\u2010up in both groups. NYHA (\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      =\u00a0.030), LVEF (\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      =\u00a0.013), and LVEDD (\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      =\u00a0.003) improved in patients with HBP compared with BVP.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>HBP was safe and more effective in improving the cardiac function and remodeling in patients with brady\u2010arrhythmias, permanent AF and HFrEF compared with BVP.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pace.14289","type":"journal-article","created":{"date-parts":[[2021,6,3]],"date-time":"2021-06-03T09:05:21Z","timestamp":1622711121000},"page":"1193-1199","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Brady\u2010arrhythmias in patients with atrial fibrillation and heart failure of reduced ejection fraction: is his\u2010bundle pacing superior to biventricular pacing\uff1f"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3579-8000","authenticated-orcid":false,"given":"Pei\u2010pei","family":"Ma","sequence":"first","affiliation":[{"name":"Department of Cardiology The First Affiliated Hospital of Dalian Medical University  Dalian Liaoning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi\u2010heng","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Cardiology The First Affiliated Hospital of Dalian 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