{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:49:54Z","timestamp":1747187394260,"version":"3.40.5"},"reference-count":21,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,7,16]],"date-time":"2021-07-16T00:00:00Z","timestamp":1626393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To compare the outcome of paroxysmal atrial fibrillation (AF) ablation via pulmonary vein isolation using Ablation Index (AI) with strict or standard stability criteria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We enrolled 130 consecutive naive patients affected by paroxysmal AF who underwent PVI at two high\u2010volume centers. AI target was \u2265380 at the posterior wall and \u2265500 at the anterior wall. Strict versus standard stability criteria were set for Group 1 (65 patients) and Group 2 (65 patients), respectively. We compared those strategies with a historical cohort of 72 consecutive patients treated at same centers in the VISITALY study, using average force \u226510\u00a0g and strict stability criteria as target parameters. Interlesion distance target was\u00a0&lt;6\u00a0mm. Recurrence was defined as any AF, atrial tachycardia (AT) or atrial flutter (AFL) during the 12 months after ablation, excluding a 90\u2010days blanking period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Procedure duration (224.05 \u00b1 47.21 vs. 175.61 \u00b1 51.29\u00a0min; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001), fluoroscopy time (11.85 \u00b1 4.38 vs. 10.46 \u00b1 6.49\u00a0min; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.019) and pericardial effusion rate (9.23% vs. 0%; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.01) were higher in Group 1 than in Group 2. Freedom from AF\/AT\/AFL at 12 months was not significantly different (Group 1: 86.15%; Group 2: 90.77%; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.42). Compared to VISITALY study, there were not significant differences in terms of recurrences.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A strategy of PVI using AI with standard stability criteria performed the best in terms of procedure efficiency and safety. Twelve\u2010months arrhythmia\u2010free survival rate was comparable with other strategies pursuing an interlesion distance target\u00a0&lt;6\u00a0mm, regardless of the use of AI.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.14309","type":"journal-article","created":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T14:23:01Z","timestamp":1625494981000},"page":"1404-1412","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Standard versus strict stability criteria in radiofrequency paroxysmal atrial fibrillation ablation using ablation index"],"prefix":"10.1111","volume":"44","author":[{"given":"Giulio","family":"Zucchelli","sequence":"first","affiliation":[{"name":"Second Division of Cardiology Pisa University Hospital  Pisa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matteo","family":"Parollo","sequence":"additional","affiliation":[{"name":"Second Division of Cardiology Pisa University Hospital  Pisa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabrizio","family":"Guarracini","sequence":"additional","affiliation":[{"name":"Department of Cardiology Santa Chiara Hospital  Trento Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9388-3292","authenticated-orcid":false,"given":"Massimiliano","family":"Marini","sequence":"additional","affiliation":[{"name":"Department of Cardiology Santa Chiara Hospital  Trento Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Di Cori","sequence":"additional","affiliation":[{"name":"Second Division of Cardiology Pisa University Hospital  Pisa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina","family":"Barletta","sequence":"additional","affiliation":[{"name":"Second Division of Cardiology Pisa University Hospital  Pisa 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