{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T03:31:06Z","timestamp":1762918266559,"version":"3.40.5"},"reference-count":17,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2021,9,17]],"date-time":"2021-09-17T00:00:00Z","timestamp":1631836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims and methods<\/jats:title><jats:p>In case of cardiacimplantable electronicdevice (CIED)\u2010related infections, it is mandatory to completely remove the device and administer prolonged antibiotic therapy. The management of patients explanted for an implantable defibrillator (ICD) infection is complex especially in patients needing anti\u2010bradycardia pacing or tachyarrhythmia protection. We tested the efficacy and safety of a conventional ICD externally connected to a transvenous dual\u2010coil lead as bridging therapy before the reimplant, comparing outcomes with a historical cohort of patients (N\u00a0=\u00a0113) treated with temporary transvenous pacing. We enrolled 18 patients explanted for ICD infection and needing prolonged antibiotic therapy in three high\u2010volume Italian centers. They received an external ICD stand\u2010by for a mean of 16.5 (4\u201330) days before the reimplant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No patient experienced malfunction of the system, with a significant reduction of this complication versus temporary transfemoral pacing (37%, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.004). Post\u2010procedural occurrence of other complications (infection, relevant local bleeding, ventricular tachycardia during insertion of the lead, cardiac perforation, and venous thromboembolism) was low and not different in the two groups. One patient experienced an electrical storm, effectively recognized by the external ICD and treated with anti\u2010tachycardia pacings (ATPs) and shocks.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>An approach with an external ICD seems to be a safe and viable option as bridging therapy in patients requiring ICD explant for CIED infection.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.14355","type":"journal-article","created":{"date-parts":[[2021,9,9]],"date-time":"2021-09-09T09:18:49Z","timestamp":1631179129000},"page":"1884-1889","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Management of patients explanted for implantable cardioverter defibrillator infections: Bridge therapy with external temporary ICD"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7517-0771","authenticated-orcid":false,"given":"Gabriele","family":"Dell'Era","sequence":"first","affiliation":[{"name":"Division of Cardiology, University of Eastern Piedmont Maggiore della Carit\u00e0 Hospital  Novara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0435-1142","authenticated-orcid":false,"given":"Eleonora","family":"Prenna","sequence":"additional","affiliation":[{"name":"Division of Cardiology Ss. Trinit\u00e0 Hospital  Borgomanero Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3617-2739","authenticated-orcid":false,"given":"Matteo","family":"Ziacchi","sequence":"additional","affiliation":[{"name":"Institute of Cardiology, University of Bologna S. Orsola\u2010Malpighi University Hospital  Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Igor","family":"Diemberger","sequence":"additional","affiliation":[{"name":"Institute of Cardiology, University of Bologna S. Orsola\u2010Malpighi University Hospital  Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Varalda","sequence":"additional","affiliation":[{"name":"Division of Cardiology Santi Antonio e Biagio e Cesare Arrigo Hospital  Alessandria Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Guerra","sequence":"additional","affiliation":[{"name":"Cardiology and Arrhythmology Clinic, Department of Biomedical Sciences and Public Health Marche Polytechnic University  Ancona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauro","family":"Biffi","sequence":"additional","affiliation":[{"name":"Institute of Cardiology, University of Bologna S. Orsola\u2010Malpighi University Hospital  Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eraldo","family":"Occhetta","sequence":"additional","affiliation":[{"name":"Division of Cardiology Sant'Andrea Hospital  Vercelli Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Patti","sequence":"additional","affiliation":[{"name":"Division of Cardiology, University of Eastern Piedmont Maggiore della Carit\u00e0 Hospital  Novara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,9,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eux258"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2017-311638"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.7326\/M15-2732"},{"key":"e_1_2_7_5_1","first-page":"382","article-title":"Impact on all\u2010cause and cardiovascular mortality of cardiac implantable electronic device complications results from the POINTED Registry","volume":"6","author":"Palmisano P","year":"2020","journal-title":"J Am Coll Cardiol EP"},{"key":"e_1_2_7_6_1","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1093\/europace\/euz246","article-title":"European Heart Rhythm Association (EHRA) international consensus document on how to prevent, diagnose, and treat cardiac implantable electronic device infections\u2014endorsed by the Heart Rhythm Society (HRS), the Asia Pacific Heart Rhythm Society (APHRS), the Latin American Heart Rhythm Society (LAHRS), International Society for Cardiovascular Infectious Diseases (ISCVID) and the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) in collaboration with the European Association for Cardio\u2010Thoracic Surgery (EACTS)","volume":"22","author":"Blomstrom\u2010Lundqvist C","year":"2020","journal-title":"Europace"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.12175"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2006.00454.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eut045"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.003042"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu112"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2009.02590.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9592.2003.00311.x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.04.016"},{"key":"e_1_2_7_15_1","first-page":"1726","article-title":"External implantable defibrillator as a bridge to reimplant after implantable cardioverter\u2010defibrillator explant","volume":"17","author":"Dell'Era G","year":"2015","journal-title":"Europace"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.13320"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(82)90505-7"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.1818"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.14355","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pace.14355","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.14355","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T05:56:23Z","timestamp":1693202183000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pace.14355"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,17]]},"references-count":17,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["10.1111\/pace.14355"],"URL":"https:\/\/doi.org\/10.1111\/pace.14355","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"type":"print","value":"0147-8389"},{"type":"electronic","value":"1540-8159"}],"subject":[],"published":{"date-parts":[[2021,9,17]]},"assertion":[{"value":"2021-03-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}