{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T03:31:20Z","timestamp":1762918280223,"version":"3.40.5"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,12,10]],"date-time":"2021-12-10T00:00:00Z","timestamp":1639094400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Data regarding the use of high\u2010power short\u2010duration (HPSD) radiofrequency (RF) in combination with half\u2010normal saline irrigation for catheter irrigation are limited.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study investigated the safety and efficacy of using HPSD RF ablation in combination with half\u2010normal saline irrigation for the treatment of AF.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>One hundred consecutive patients with AF underwent RF ablation using HPSD combined with half\u2010normal saline for catheter irrigation. In addition, the following ablation strategies were used: 1 mm tags for the display of ablation lesions on the mapping system, high\u2010frequency jet ventilation (HFJV), low contact force, pacing after ablation to verify areas of noncapture, atrial\/ventricular pacing at 500 to 700\u00a0ms to aid in catheter stability, use of two skin electrodes to reduce impedance, and postablation adenosine infusion. Power was started at 40 to 45 W and was modulated manually based on impedance changes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The average age of patients was 65.2 years and 70% were male. Forty seven percent had paroxysmal AF and the average CHA<jats:sub>2<\/jats:sub>DS<jats:sub>2<\/jats:sub>\u2010VASc score was 2.1 \u00b1 1.6. The average power and lesion duration were 38.1 \u00b1 3.3 W and 8.1 \u00b1 2.3 s, respectively. During a median follow\u2010up period of 321 \u00b1 139 days, 89% of the patients remained free from any atrial arrhythmias after a single RF ablation procedure. No procedure\u2010related death, stroke, pericardial effusion, or atrioesophageal fistula occurred during follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Catheter ablation using HPSD RF lesions in combination with half\u2010normal saline irrigation and is safe and effective, and results in high rate of freedom from AF.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.14407","type":"journal-article","created":{"date-parts":[[2021,11,12]],"date-time":"2021-11-12T12:44:53Z","timestamp":1636721093000},"page":"43-49","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Outcome of high\u2010power short\u2010duration radiofrequency ablation in combination with half\u2010normal saline irrigation for the treatment of atrial fibrillation"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1241-4054","authenticated-orcid":false,"given":"Abhishek","family":"Maan","sequence":"first","affiliation":[{"name":"Cardiac Arrhythmia Unit, Heart Center Massachusetts General Hospital  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weeranun D.","family":"Bode","sequence":"additional","affiliation":[{"name":"Cardiac Arrhythmia Unit, Heart Center Massachusetts General Hospital  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. Kevin","family":"Heist","sequence":"additional","affiliation":[{"name":"Cardiac Arrhythmia Unit, Heart Center Massachusetts General Hospital  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grace","family":"Ha","sequence":"additional","affiliation":[{"name":"Cardiac Arrhythmia Unit, Heart Center Massachusetts General Hospital  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony","family":"Carnicelli","sequence":"additional","affiliation":[{"name":"Duke University Hospital\/Duke Clinical Research Institute  Durham North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathryn","family":"Slattery","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, Critical Care and Pain Medicine Massachusetts General Hospital  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Fitzsimons","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, Critical Care and Pain Medicine Massachusetts General Hospital  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeremy","family":"Ruskin","sequence":"additional","affiliation":[{"name":"Cardiac Arrhythmia Unit, Heart Center Massachusetts General Hospital  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moussa","family":"Mansour","sequence":"additional","affiliation":[{"name":"Cardiac Arrhythmia Unit, Heart Center Massachusetts General Hospital  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,12,10]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.0693"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1707855"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.019406"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.014092"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2018.11.031"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.13185"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2018.06.021"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12758"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2017.02.030"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euy031"},{"key":"e_1_2_9_12_1","first-page":"8740","article-title":"Five seconds of 50\u201360 W radiofrequency atrial ablations were transmural and safe: an in vitro mechanistic assessment and force\u2010controlled in vivo validation","volume":"19","author":"Bhaskaran A","year":"2017","journal-title":"Europace"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.14110"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.82.3.1034"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12682"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.13363"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.110.957761"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2018.08.016"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)60026-5"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2012.02.015"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2009.11.011"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2015.10.023"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12830"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.13721"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2015.08.029"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.07.770"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.05.061"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.01.014"},{"key":"e_1_2_9_29_1","first-page":"271","article-title":"Discrepant electrophysiological characteristics and calcium homeostasis of left anterior and posterior myocyctes","volume":"23","author":"Suenari K","year":"2012","journal-title":"J Cardiovascular Electrophysiol"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2016.11.013"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2017.11.018"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.14407","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pace.14407","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.14407","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T11:59:09Z","timestamp":1693223949000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pace.14407"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,10]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["10.1111\/pace.14407"],"URL":"https:\/\/doi.org\/10.1111\/pace.14407","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"type":"print","value":"0147-8389"},{"type":"electronic","value":"1540-8159"}],"subject":[],"published":{"date-parts":[[2021,12,10]]},"assertion":[{"value":"2021-05-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}