{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:50:17Z","timestamp":1747187417824,"version":"3.40.5"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,5,2]],"date-time":"2022-05-02T00:00:00Z","timestamp":1651449600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The risk of Cardiac Implantable Electronic Device (CIED) infection has been increasing in recent years. For pacemaker\u2010dependent patients, a temporary pacemaker is needed before a new device can be implanted. The aim of this study is to evaluate the safety and efficacy of using a temporary pacing device with an externalized active fixation lead (bridge pacemaker) before a new device can be implanted in pacemaker\u2010dependent patients with device infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All patients who were admitted to our cardiac center with CIED infection and in need of bridge pacemaker implantation from April 2013 to August 2020 were prospectively enrolled in this observational study. The medical records of all patients were collected and evaluated. All procedure\u2010related complications were also collected. Long\u2010term outcomes, including reinfection and death within 1 year after hospital discharge, were collected through telephone follow\u2010ups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During the study period, 1050 patients underwent CIED extraction, of which 312 pacemaker\u2010dependent patients underwent bridge pacemaker implantation. The mean age of the extracted leads was 44 \u00b1 38.7 months. The bridge pacemakers were in use for a mean duration of 6 days. Nine patients developed procedure\u2010related complications including pericardial tamponade, pneumothorax, peripheral venous thrombosis, and pulmonary embolism. Three patients developed complications that were related to their bridge pacemakers, including lead dislodgement, over\u2010sensing and elevated pacing threshold. During the 1\u2010year follow\u2010up, it was found that four patients had developed CIED reinfection and three patients had died due to cardiac\u2010related reasons.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A bridge pacemaker with an externalized active fixation lead is safe and efficacious for pacemaker\u2010dependent patients with device infection.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.14493","type":"journal-article","created":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T14:08:58Z","timestamp":1648735738000},"page":"761-767","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Bridge pacemaker with an externalized active fixation lead for pacemaker\u2010dependent patients with device infection"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2857-2188","authenticated-orcid":false,"given":"Zengli","family":"Xiao","sequence":"first","affiliation":[{"name":"Intensive Care Unit Peking University People's Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinshan","family":"He","sequence":"additional","affiliation":[{"name":"Cardiovascular Department Peking University People's Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dandan","family":"Yang","sequence":"additional","affiliation":[{"name":"Cardiovascular Department Peking University People's Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youzhong","family":"An","sequence":"additional","affiliation":[{"name":"Intensive Care Unit Peking University People's Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuebin","family":"Li","sequence":"additional","affiliation":[{"name":"Cardiovascular Department Peking University People's Hospital  Beijing 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