{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T03:03:55Z","timestamp":1784516635727,"version":"3.55.0"},"reference-count":53,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,6,13]],"date-time":"2022-06-13T00:00:00Z","timestamp":1655078400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The electrophysiological discrimination between fast\u2010slow (F\/S\u2010) atrioventricular (AV) nodal reentrant tachycardia (NRT) and atrial tachycardia (AT) originating from the interatrial septum remains challenging. While a V\u2010A\u2010A\u2010V response may occur immediately after ventricular induction or entrainment of either tachycardia, the electrophysiological dissimilarities in that response between the two tachycardias remain unclear. The purpose of this study was to identify a diagnostic indicator discriminating F\/S\u2010AVNRT from AT by examining the difference in the V\u2010A\u2010A\u2010V response between the two tachycardias.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective study included 17 patients with F\/S\u2010AVNRT [seven with common\u2010form F\/S\u2010AVNRT using a typical slow pathway (SP) and 10 with superior type F\/S\u2010AVNRT using a superior SP] and 10 patients with reentrant AT. All 27 patients presented with long RP supraventricular tachycardia and an initial V\u2010A\u2010A\u2010V response upon ventricular induction or entrainment. The V\u2010A\u2010A\u2010V response in patients with F\/S\u2010AVNRT was due to dual atrial responses. We measured the interval between the first (A1) and second atrial electrogram (A2) of V\u2010A\u2010A\u2010V and calculated \u0394AA by subtracting A1\u2010A2 from the tachycardia cycle length.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>V\u2010A\u2010A\u2010V responses were observed most often upon ventricular induction of F\/S\u2010AVNRT (6 \u00b1 5 times) as well as AT (6 \u00b1 6 times; <jats:italic>p\u00a0<\/jats:italic>=\u00a0.87). The V\u2010A\u2010A\u2010V response upon ventricular entrainment was observed in a single patient with F\/S\u2010AVNRT versus 10 all patients with AT (<jats:italic>p\u00a0<\/jats:italic>&lt;\u00a0.001). \u0394AA ranged between \u221280 and 228\u00a0ms in F\/S\u2010AVNRT and between \u2212184 and 26\u00a0ms in AT. A \u0394AA\u00a0&gt;\u00a026\u00a0ms predicted a diagnosis of F\/S\u2010AVNRT with a 76% sensitivity and 100% specificity, while a \u0394AA\u00a0&lt;\u221280\u00a0ms predicted a diagnosis of AT with a 50% sensitivity and 100% specificity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>\u0394AA is a useful, confirmatory, diagnostic indicator of F\/S\u2010AVNRT versus AT associated with the V\u2010A\u2010A\u2010V response.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.14540","type":"journal-article","created":{"date-parts":[[2022,6,5]],"date-time":"2022-06-05T04:54:46Z","timestamp":1654404886000},"page":"839-852","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Discrimination of atypical atrioventricular nodal reentrant tachycardia from atrial tachycardia by the V\u2010A\u2010A\u2010V response"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9611-2303","authenticated-orcid":false,"given":"Yoshiaki","family":"Kaneko","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine Gunma University Graduate School of Medicine  Maebashi Gunma Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9635-2769","authenticated-orcid":false,"given":"Tadashi","family":"Nakajima","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Gunma University Graduate School of Medicine  Maebashi Gunma Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuntaro","family":"Tamura","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Gunma University Graduate School of Medicine  Maebashi Gunma 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