{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T11:01:29Z","timestamp":1785841289984,"version":"3.56.0"},"reference-count":30,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T00:00:00Z","timestamp":1654128000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Atrial pacing (AP) can unmask or aggravate a preexisting interatrial block (IAB). The aim of our study was to determine whether AP is associated with the development of atrial high\u2010rate episodes (AHRE) during follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with dual\u2010chamber cardiac implantable electronic devices (CIEDs), no previous documented atrial fibrillation, and with a 6\u2010month minimum follow\u2010up were included. In all patients, sinus and paced P\u2010wave duration were measured. AHRE was defined as an episode of atrial rate \u2265225\u00a0bpm with a minimum duration of 5\u00a0min, excluding those documented during the first 3\u00a0months after implantation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 220 patients were included (75\u00a0\u00b1\u00a010 years, 61% male). After a mean follow\u2010up of 59\u00a0\u00b1\u00a025\u00a0months, 46% of patients presented AHRE. Mean paced P\u2010wave duration was significantly longer than the sinus P\u2010wave duration (154\u00a0\u00b1\u00a027 vs. 115\u00a0\u00b1\u00a018\u00a0ms; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001). Sinus and paced P\u2010waves were significantly longer in those who developed AHRE (sinus: 119\u00a0\u00b1\u00a020 vs. 112\u00a0\u00b1\u00a016; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.006; paced: 161\u00a0\u00b1\u00a029 vs. 148\u00a0\u00b1\u00a023; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001). A paced P\u2010wave \u2265160\u00a0ms was the best predictor of AHRE, especially those lasting &gt;24\u00a0h (odds ratio [OR] 4.2 [95% confidence interval (CI)] [1.6\u201311.4]; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.004).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>AP significantly prolongs P\u2010wave duration and is associated with further development of AHRE. A paced P\u2010wave \u2265160\u00a0ms is a strong predictor of AHRE and should be taken into consideration as a new definition of IAB in the presence of AP.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.14541","type":"journal-article","created":{"date-parts":[[2022,5,26]],"date-time":"2022-05-26T05:55:42Z","timestamp":1653544542000},"page":"832-838","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Paced P\u2010wave duration as a significant predictor for atrial high\u2010rate episodes in patients with cardiac implantable electronic devices"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6159-6472","authenticated-orcid":false,"given":"Jos\u00e9 M. Rubio","family":"Campal","sequence":"first","affiliation":[{"name":"Arrhythmia Unit, Cardiology Department Fundaci\u00f3n Jim\u00e9nez D\u00edaz \u2013 Quir\u00f3n Salud  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto S\u00e1nchez","family":"Arjona","sequence":"additional","affiliation":[{"name":"Arrhythmia Unit, Cardiology Department Fundaci\u00f3n Jim\u00e9nez D\u00edaz \u2013 Quir\u00f3n Salud  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila S. Garc\u00eda","family":"Talavera","sequence":"additional","affiliation":[{"name":"Arrhythmia Unit, Cardiology Department Fundaci\u00f3n Jim\u00e9nez D\u00edaz \u2013 Quir\u00f3n Salud  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loreto Bravo","family":"Calero","sequence":"additional","affiliation":[{"name":"Arrhythmia Unit, Cardiology Department Fundaci\u00f3n Jim\u00e9nez D\u00edaz \u2013 Quir\u00f3n Salud  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla L\u00e1zaro","family":"Rivera","sequence":"additional","affiliation":[{"name":"Arrhythmia Unit, Cardiology Department Fundaci\u00f3n Jim\u00e9nez D\u00edaz \u2013 Quir\u00f3n Salud  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco D\u00edaz","family":"Cortegana","sequence":"additional","affiliation":[{"name":"Arrhythmia Unit, Cardiology Department Fundaci\u00f3n Jim\u00e9nez D\u00edaz \u2013 Quir\u00f3n Salud  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Tu\u00f1\u00f3n","sequence":"additional","affiliation":[{"name":"Arrhythmia Unit, Cardiology Department Fundaci\u00f3n Jim\u00e9nez D\u00edaz \u2013 Quir\u00f3n Salud  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adri\u00e1n M.","family":"Baranchuk","sequence":"additional","affiliation":[{"name":"Department of Medicine Kingston General Hospital, Queen's University  Kingston Ontario 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