{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:50:22Z","timestamp":1747187422415,"version":"3.40.5"},"reference-count":19,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T00:00:00Z","timestamp":1655424000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Guidelines recommend that cardiac pacing should be considered in patients suffering from frequent vasovagal syncopal (VVS) episodes. Studies have demonstrated the safety and efficacy of leadless pacemakers (LP) in cardioinhibitory vasovagal populations specifically, rendering them a reasonable alternative to transvenous pacing in these patients. However, due to the paucity of data on extraction and the number of concomitant LPs that can be safely implanted, there are concerns regarding LPs\u2019 battery longevity, especially in younger patients who may require decades of pacing therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a retrospective analysis of the first 100 LPs implanted at a tertiary cardiac centre in the UK. Demographical data and device parameters at implant and follow\u2010ups were obtained from the hospital's medical records. The battery life of the LPs in the VVS patients was compared to that of patients with other pacing indications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ninety patients were included in the analysis. 14 patients (15.6%) had VVS, and 76 patients (84.4%) had other indications for pacing. Mean ages were 34 \u00b1 13 years and 62 \u00b1 20 years for the VVS and the other group, respectively. The estimated total battery life was 15.22 \u00b1 0.35 and 13.65 \u00b1 2.97 years in the VVS and the other indications group respectively (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.04). There were no complications in the VVS group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>LPs provide a promising treatment for patients with vasovagal syncope with reassuring battery performance at the short\/intermediate term. Further longer\u2010term follow\u2010up data are needed to identify the true battery potential in this patient cohort.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.14546","type":"journal-article","created":{"date-parts":[[2022,6,12]],"date-time":"2022-06-12T15:08:05Z","timestamp":1655046485000},"page":"874-884","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A leadless pacemaker matched with a vasovagal syncope: how long can it last?"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8481-1940","authenticated-orcid":false,"given":"Mohamed","family":"ElRefai","sequence":"first","affiliation":[{"name":"Cardiac Rhythm Management Research Department University Hospital Southampton NHS Foundation Trust  Southampton UK"},{"name":"Faculty of Medicine University of Southampton  Southampton UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1702-4346","authenticated-orcid":false,"given":"Christina","family":"Menexi","sequence":"additional","affiliation":[{"name":"Cardiac Rhythm Management Research Department University Hospital Southampton NHS Foundation Trust  Southampton UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Abouelasaad","sequence":"additional","affiliation":[{"name":"Cardiac Rhythm Management Research Department University Hospital Southampton NHS Foundation Trust  Southampton UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Nettey","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Southampton  Southampton UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul R.","family":"Roberts","sequence":"additional","affiliation":[{"name":"Cardiac Rhythm Management Research Department University Hospital Southampton NHS Foundation Trust  Southampton UK"},{"name":"Faculty of Medicine University of Southampton  Southampton 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