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Phenytoin has well\u2010studied sodium\u2010channel blocking abilities which can be taken advantage of to treat ventricular arrhythmias. Thus, it should remain in the arsenal of antiarrhythmics for any electrophysiologist. We present two cases of intractable ventricular arrhythmia in children that were controlled with phenytoin at supra\u2010therapeutic serum levels, preventing the need for heart transplantation.<\/jats:p>","DOI":"10.1111\/pace.14565","type":"journal-article","created":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T08:38:33Z","timestamp":1659083913000},"page":"1385-1389","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Use of supra\u2010therapeutic phenytoin for management of ventricular arrhythmias in children: Case series and literature review"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3166-2870","authenticated-orcid":false,"given":"Suneet","family":"Bhansali","sequence":"first","affiliation":[{"name":"Division of Pediatric Cardiology NYU Langone Health  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reina Bianca M.","family":"Tan","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology NYU Langone Health  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Spilios","sequence":"additional","affiliation":[{"name":"Department of Pharmacy NYU Langone Health  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Cecchin","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology NYU Langone Health  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,8,15]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-017-8391-5"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-015-7967-1"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/med.2610030403"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrcr.2016.10.001"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(75)90331-2"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.13343"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1984.02140470064021"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(85)80279-5"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.118.035455"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2015-209521"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2020.04.027"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.5694\/mja13.10224"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1960.03840120030004"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/FJC.0b013e3181bfaddc"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.14565","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pace.14565","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.14565","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T05:08:27Z","timestamp":1692508107000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pace.14565"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,15]]},"references-count":14,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1111\/pace.14565"],"URL":"https:\/\/doi.org\/10.1111\/pace.14565","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"value":"0147-8389","type":"print"},{"value":"1540-8159","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,15]]},"assertion":[{"value":"2021-12-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}