{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T10:33:09Z","timestamp":1759401189092,"version":"3.40.5"},"reference-count":20,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,9,23]],"date-time":"2022-09-23T00:00:00Z","timestamp":1663891200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>Our objective was to explore whether the accuracy of the transitional zone index (TZI) for outflow tract ventricular arrhythmias (OT\u2010VAs) origin is affected by cardiac rotation and the additive value of interventricular septum angle (IVSa) obtained from coronary computed tomography angiography (CCTA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Standard 12\u2010lead ECGs of OT\u2010VAs with inferior axis in consecutive patients undergoing both CCTA examination and successful ablation were retrospectively analyzed. The IVSa was defined as an angle between the long axis of IVS and sagittal axis of the body from CCTA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>64 patients (31 men; mean age 54.2\u00a0\u00b1\u00a011.6 years) were enrolled. The OT\u2010VAs exhibited right ventricular outflow tract origin in 46 (71.9%) patients and 36 (78.3%) were diagnosed correctly by TZI. The left ventricular outflow tract origin OT\u2010VAs was observed in 18 (28.1%) patients and 16 (88.9%) were diagnosed correctly by TZI. The patients were then divided into TZI correct group (<jats:italic>n<\/jats:italic>\u00a0=\u00a052) and TZI incorrect group (<jats:italic>n<\/jats:italic>\u00a0=\u00a012). In the TZI incorrect group, 11\/12 (91.7%) cases were R\/S transition in lead V3 with the TZ score during premature ventricular contractions [2.8(2.5\u22123.4)], and the TZI between \u22121.5 and 0. The IVSa was significantly larger in the TZI incorrect group than correct group (52.0\u00a0\u00b1\u00a06.9\u00b0 vs. 39.0\u00a0\u00b1\u00a06.1\u00b0; <jats:italic>p<\/jats:italic> &lt;\u00a0.0001). The IVSa \u226546\u00b0 predicted TZI incorrect with 92% sensitivity, 94% specificity, and 94% accuracy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The IVSa is a novel cardiac rotation index that reliably improves TZI to differentiate the OT\u2010VAs origin, especially for the OT\u2010VAs with lead V3 R\/S transition.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.14593","type":"journal-article","created":{"date-parts":[[2022,9,15]],"date-time":"2022-09-15T10:14:56Z","timestamp":1663236896000},"page":"1279-1287","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Interventricular septum angle obtained from cardiac computed tomography for origin differentiation of outflow tract ventricular arrhythmia between left and right"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7591-9930","authenticated-orcid":false,"given":"Xiaomei","family":"Zhu","sequence":"first","affiliation":[{"name":"Department of Radiology, the First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital)  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shumin","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Cardiology the First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital)  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kefan","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Radiology, the First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital)  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zenghong","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Cardiology the First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital)  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Cardiology the First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital)  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0139-2352","authenticated-orcid":false,"given":"Zhixin","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Cardiology the First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital)  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,9,23]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-809657-4.99778-3"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01767-3"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.01.035"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2010.11.023"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12392"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hroo.2021.07.009"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.119.007392"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.06.076"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2013.09.018"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2019-314748"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/anec.12516"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.15420\/aer.2020.10"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2008.02.009"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.10.037"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.05.021"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-0736(91)90029-L"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.13493"},{"key":"e_1_2_12_19_1","first-page":"e006243","article-title":"V3R\/V7 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