{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T05:34:27Z","timestamp":1775021667286,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,12,27]],"date-time":"2022-12-27T00:00:00Z","timestamp":1672099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Although premature atrial contractions (PACs) just after catheter ablation (CA) for atrial fibrillation (AF) are common, their clinical significance is uncertain. This study aimed to evaluate whether the PAC burden after an initial CA for AF was associated with late recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We enrolled 346 patients with AF (median age, 65 years; 30% female; 57% with paroxysmal AF) who underwent an initial radiofrequency CA and a 24\u2010h Holter monitoring the day after the procedure. PAC was defined as supraventricular complexes occurring \u226530% earlier than expected compared with a previous RR interval, and the number of PAC\/24\u00a0h during post\u2010procedural Holter monitoring was analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>AF recurred in 106 patients (31%) during a median follow\u2010up of 19 months. These patients had significantly more PAC\/24\u00a0h than those without (median [interquartile range], 891 [316\u20134351] beats vs. 409 [162\u20131,303] beats; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.01). The number of PACs was independently associated with AF recurrence after adjustment for clinical parameters and left atrial (LA) enlargement. Receiver operating characteristic (ROC) curve analysis revealed that 1431 PAC\/24\u00a0h was the optimal cut\u2010off value for predicting AF recurrence. Adding the PAC\/24\u00a0h to the prediction model with LA diameter appeared to correctly reclassify patients who were thought to be at high risk for AF recurrence into the low\u2010risk group and vice versa.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The number of PACs was an independent risk factor for AF recurrence. A 24\u2010h Holter recording the day after an initial CA is a simple and beneficial tool for the risk stratification of AF recurrence.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.14648","type":"journal-article","created":{"date-parts":[[2022,12,16]],"date-time":"2022-12-16T11:53:31Z","timestamp":1671191611000},"page":"152-160","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Premature atrial contraction immediately after catheter ablation was associated with late recurrence of atrial fibrillation"],"prefix":"10.1111","volume":"46","author":[{"given":"Tomoki","family":"Fujisawa","sequence":"first","affiliation":[{"name":"Division of Cardiology Department of Cardiology Pulmonology Hypertension, and Nephrology Ehime University Graduate School of Medicine  Ehime 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