{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T17:01:17Z","timestamp":1784134877807,"version":"3.55.0"},"reference-count":29,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,4,7]],"date-time":"2023-04-07T00:00:00Z","timestamp":1680825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Outcomes of transvenous lead extraction (TLE) are well reported in the general population, However, data on safety, efficacy of TLE in octogenarians with a long lead dwell time, using powered extraction tools are limited. The aim of this multicenter study was to evaluate the safety, effectiveness of TLE in octogenarians using the bidirectional rotational mechanical sheaths and mid\u2010term outcome after TLE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study population comprised 83 patients (78.3% male; mean age 85\u00a0\u00b1\u00a03\u00a0years; [range 80\u201394\u00a0years]) with 181 target leads. All the leads (mean implant duration 112\u00a0\u00b1\u00a077\u00a0months [range 12\u2013377]) were extracted exclusively using the Evolution RL sheaths (Cook Medical, Bloomington, IN, USA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The main indication for TLE was infection in 84.3% of cases. Complete procedural success rate, clinical success rate, per lead were 93.9% and 98.3%, respectively. Failure of lead extraction was seen in 1.7% of leads. The additional use of a snare was required in 8.4% of patients. Major complications occurred in one patient (1.2%). Thirty\u2010day mortality after TLE was 6%. During a mean time follow\u2010up of 22\u00a0\u00b1\u00a021\u00a0months, 24 patients (29%) died. No procedure\u2010related mortality occurred. Predictors of mortality included ischemic cardiomyopathy (HR 4.35; 95% CI 1.87\u201310.13; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.001), left ventricularejection fraction \u226435% (HR 7.89; 95% CI 3.20\u201319.48; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001), and TLE for systemic infection (HR 4.24; 95% CI 1.69\u201310.66; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.002).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>At experienced centers bidirectional rotational mechanical sheaths combined with different mechanical tools and femoral approach allowreasonable success and safety in octogenarian with long lead dwell time. Patient's age should not influence the decision to extract or not the leads, although the 30\u2010day and mid\u2010term mortality are significant, especially in the present of specific comorbidities.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.14696","type":"journal-article","created":{"date-parts":[[2023,3,23]],"date-time":"2023-03-23T09:55:26Z","timestamp":1679565326000},"page":"960-968","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Outcomes of transvenous lead extraction in octogenarians using bidirectional rotational mechanical sheaths"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8574-9421","authenticated-orcid":false,"given":"Federico","family":"Migliore","sequence":"first","affiliation":[{"name":"Department of Cardiac, Thoracic, Vascular Sciences and Public Health University of Padova  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