{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:19:34Z","timestamp":1787015974656,"version":"build-2736575974"},"reference-count":32,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T00:00:00Z","timestamp":1685491200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Over the past years, mapping and ablation techniques for the treatment of ventricular tachycardia (VT) have evolved rapidly. High Density (HD) substrate mapping is now routine and pre\u2010procedural imaging is increasingly used. The additional value of these techniques for long\u2010term VT\u2010free survival is not clear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We compared baseline and procedural characteristics, procedural success, safety and outcome of mapping and ablation of ventricular tachycardia in patients with ischemic heart disease between two groups. (1) Low Density (LD) group: VT mapping and ablation with a 4\u00a0mm single tip catheter (2) HD group: HD substrate mapping with the Pentaray (Biosense Webster, USA) or HD Grid (Abbott, USA) catheter and ablation with a 4\u00a0mm single tip catheter.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      VT ablation was performed in 133 patients (71 patients in LD group and 62 patients in HD group). The median follow\u2010up was 5.0 years in LD group and 2.0 years in HD group. One\u2010, two\u2010, and five\u2010year VT recurrence rates were 47%, 56%, and 65% in the LD group versus 39%, 50%, and 55% in the HD group (log\u2010rank test for VT recurrence\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.70). One\u2010, two\u2010, and five\u2010year ICD shock recurrence rates were 14%, 18%, and 24% in the LD group versus 8%, 15%, and 19% in the HD group (log\u2010rank test for ICD\u2010shock\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.79). All\u2010cause mortality, cardiac (non\u2010arrhythmic), and arrhythmic death, were similar in both groups. Severe procedural complications (tamponade, stroke, or procedural death) occurred in four patients (5%, 1 vascular, 3 tamponade) in the LD group versus two patients (3%, both tamponade) in the HD group (NS). In univariate and multivariable analysis, only a higher LVEF was significantly associated with VT\u2010free survival. HD mapping was not significantly associated with VT\u2010free survival. Anterior infarct location and age were significantly associated with ICD recurrent shock in both univariate and multivariable analyses.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In patients with ischemic cardiomyopathy, a HD substrate mapping, and ablation strategy did not lead to higher VT\u2010free survival and shock\u2010free survival compared to a single tip mapping and ablation strategy. In this study, only LVF is an independent predictor for VT recurrence. Anterior infarct location and age predict recurrent ICD shocks.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pace.14717","type":"journal-article","created":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T06:43:30Z","timestamp":1685515410000},"page":"574-582","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Long\u2010term success of a multi\u2010electrode substrate mapping and ablation strategy versus a classic single tip mapping and ablation strategy for ventricular tachycardia ablation in patients with ischemic cardiomyopathy"],"prefix":"10.1111","volume":"46","author":[{"given":"Jippe C.","family":"Balt","sequence":"first","affiliation":[{"name":"Department of Cardiology St. Antonius Hospital  Nieuwegein The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bob G. S.","family":"Abeln","sequence":"additional","affiliation":[{"name":"Department of Cardiology St. Antonius Hospital  Nieuwegein The Netherlands"},{"name":"Department of Cardiology Amsterdam University Medical Centers  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bakhtawar K.","family":"Mahmoodi","sequence":"additional","affiliation":[{"name":"Department of Cardiology Erasmus Medical Center  Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent F.","family":"van Dijk","sequence":"additional","affiliation":[{"name":"Department of Cardiology St. Antonius Hospital  Nieuwegein The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurits C. E. F.","family":"Wijffels","sequence":"additional","affiliation":[{"name":"Department of Cardiology St. Antonius Hospital  Nieuwegein The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas V. A.","family":"Boersma","sequence":"additional","affiliation":[{"name":"Department of Cardiology St. Antonius Hospital  Nieuwegein The Netherlands"},{"name":"Department of Cardiology Amsterdam University Medical Centers  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,31]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehv316"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2017.10.035"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2015.08.116"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.02.044"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2019.09.015"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eut419"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12471-020-01485-z"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.03.044"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.10.026"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61755-4"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eul109"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.114.002386"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.14740\/cr636w"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.114.002310"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eux109"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.13088"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.043216"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-020-00918-4"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.14351"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-019-00625-9"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.88.4.1647"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccep.2016.10.004"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.19102\/icrm.2019.100302"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12761"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.115.003841"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euw406"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.119.007500"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.120.008651"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2017.12.005"},{"key":"e_1_2_8_31_1","first-page":"539","article-title":"Ablation of reentry\u2010vulnerable zones determined by left ventricular activation from multiple directions: a novel approach for ventricular tachycardia ablation: a multicenter study (PHYSIO\u2010VT)","author":"Anter E","year":"2020","journal-title":"Circ Arrhythmia Electrophysiol"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.113.001404"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.114.002702"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.14717","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T18:02:54Z","timestamp":1692295374000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pace.14717"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,31]]},"references-count":32,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["10.1111\/pace.14717"],"URL":"https:\/\/doi.org\/10.1111\/pace.14717","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"value":"0147-8389","type":"print"},{"value":"1540-8159","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,31]]},"assertion":[{"value":"2022-12-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}