{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,20]],"date-time":"2025-07-20T03:59:56Z","timestamp":1752983996023,"version":"3.40.5"},"reference-count":19,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T00:00:00Z","timestamp":1686787200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>A pacemaker implantation is not indicated in cases of reversible high\u2010degree symptomatic sinus node dysfunction (SND) and atrioventricular block (AVB). However, it remains uncertain whether these reversible automaticity\/conduction disorders may recur in some patients at follow\u2010up, in the absence of reversible cause. This retrospective study aimed to determine the incidence and predictive factors of permanent pacemaker (PPM) implantation at follow\u2010up and after reversible high\u2010degree SND\/AVB.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Based on medical electronic files codes, we identified patients who were hospitalized in our cardiac intensive care unit between January 2003 and December 2020 due to reversible high\u2010degree SND\/AVB and who were discharged from the hospital alive and without PPM implantation. Acute myocardial infarction and post\u2010cardiac surgery patients were excluded. We categorized the patients according to the need for PPM at follow\u2010up due to non\u2010reversible high\u2010degree SND\/AVB.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 93 patients included, 26 patients (28%) were readmitted for PPM implantation at follow\u2010up after hospital discharge. Among baseline characteristics, compared with patients who did not have high\u2010degree SND\/AVB recurrence, those who had subsequent PPM implantation had less frequent previous hypertension (70%\u00a0vs. 46%, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.031). Regarding the initial causes of reversible SND\/AVB, isolated hyperkalemia was found more often in the patients readmitted for PPM (19%\u00a0vs. 3%\u00a0vs. <jats:italic>p<\/jats:italic>\u00a0=\u00a0.017). Moreover, recurrence of high\u2010degree SND\/AVB was significantly associated with the presence of intraventricular conduction disorders (either bundle branch block or left bundle branch hemiblock) on ECG at discharge (36% in patients without PPM vs. 68% in PPM patients, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.012).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Almost one third of the patients discharged alive from the hospital after a reversible high\u2010degree SND\/AVB needed a pacemaker implantation at follow\u2010up. Complete bundle branch block or left bundle branch hemiblock on discharge ECG after recovery of atrioventricular conduction and\/or sinus automaticity was associated with a greater risk of recurrence leading to pacemaker implantation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.14755","type":"journal-article","created":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T17:19:05Z","timestamp":1686849545000},"page":"994-1002","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Incidence and predictors of pacemaker implantation at follow\u2010up after reversible high\u2010degree sinus node dysfunction or atrioventricular block"],"prefix":"10.1111","volume":"46","author":[{"given":"Ahmed","family":"Habbout","sequence":"first","affiliation":[{"name":"Cardiology Department University Hospital  Dijon France"},{"name":"PEC 2 EA 7460 University of Burgundy and Franche\u2010Comt\u00e9  Dijon 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