{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T07:45:37Z","timestamp":1778226337174,"version":"3.51.4"},"reference-count":30,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,7,10]],"date-time":"2023-07-10T00:00:00Z","timestamp":1688947200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Automated threshold measurements (ATM) and output adaptation improved safety and follow\u2010up of cardiac implantable devices (CIED) in the last years. These algorithms were validated for conventional cardiac pacing; however, they were not suitable for permanent His Pacing. Left bundle branch area pacing (LBBAP) is an emerging technique to obtain physiologic cardiac stimulation; we tried to assess if ATM could be applied to this setting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Consecutive patients receiving ATM\u2010capable CIED and LBBAP in our hospital were enrolled in this prospective, observational trial; they were evaluated 3\u00a0months after implant, comparing pacing thresholds manually assessed and obtained via ATM. Subsequent remote follow\u2010up was carried on when available.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010five patients were enrolled. ATM for LBBAP lead provided consistent results in all the patients and was therefore activated; mean value of manually obtained LBBAP capture threshold was 0.66\u00a0\u00b1\u00a00.19\u00a0V versus ATM of 0.64\u00a0\u00b1\u00a00.19\u00a0V. TOST analysis showed equivalence of the two measures (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.66). At subsequent follow\u2010up (mean follow up 7.7\u00a0\u00b1\u00a03.2\u00a0months), ATM was effective in assessing pacing thresholds and no clinical adverse event was observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>ATM algorithms proved equivalent to manual testing in determining capture threshold and were reliably employed in patients receiving LBBAP CIED.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.14777","type":"journal-article","created":{"date-parts":[[2023,7,10]],"date-time":"2023-07-10T17:55:16Z","timestamp":1689011716000},"page":"1092-1098","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Left bundle branch area pacing (LBBAP) Auto Threshold algorithms Evaluation for Conduction System Pacing: The LATECS pilot Trial"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7130-3207","authenticated-orcid":false,"given":"Chiara","family":"Ghiglieno","sequence":"first","affiliation":[{"name":"Clinica Cardiologica Dipartimento Toraco\u2010Cardio\u2010Vascolare Ospedale Maggiore della Carit\u00e0 Novara Italy"},{"name":"Universit\u00e0 del Piemonte Orientale Amedeo Avogadro Novara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriele","family":"Dell'Era","sequence":"additional","affiliation":[{"name":"Clinica Cardiologica Dipartimento Toraco\u2010Cardio\u2010Vascolare Ospedale Maggiore della Carit\u00e0 Novara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Veroli","sequence":"additional","affiliation":[{"name":"Clinica Cardiologica Dipartimento Toraco\u2010Cardio\u2010Vascolare Ospedale Maggiore della Carit\u00e0 Novara Italy"},{"name":"Universit\u00e0 del Piemonte Orientale Amedeo Avogadro Novara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federica","family":"De Vecchi","sequence":"additional","affiliation":[{"name":"Clinica Cardiologica Dipartimento Toraco\u2010Cardio\u2010Vascolare Ospedale Maggiore della Carit\u00e0 Novara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matteo","family":"Santagostino","sequence":"additional","affiliation":[{"name":"Clinica Cardiologica Dipartimento Toraco\u2010Cardio\u2010Vascolare Ospedale Maggiore della Carit\u00e0 Novara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Porcellini","sequence":"additional","affiliation":[{"name":"Clinica Cardiologica Dipartimento Toraco\u2010Cardio\u2010Vascolare Ospedale Maggiore della Carit\u00e0 Novara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Patti","sequence":"additional","affiliation":[{"name":"Clinica Cardiologica Dipartimento Toraco\u2010Cardio\u2010Vascolare Ospedale Maggiore della Carit\u00e0 Novara Italy"},{"name":"Universit\u00e0 del Piemonte Orientale Amedeo Avogadro Novara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,7,10]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(98)01023-6"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(00)01191-7"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.04.029"},{"key":"e_1_2_10_5_1","first-page":"1","article-title":"Remote monitoring of implantable cardioverter\u2010defibrillators, cardiac resynchronization therapy and permanent pacemakers: a health technology assessment","volume":"18","author":"Health Quality Ontario","year":"2018","journal-title":"Ont Health Technol Assess Ser."},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx015"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1880-4276(11)80032-3"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euw021"},{"key":"e_1_2_10_9_1","volume-title":"Dizionario degli algoritmi dei pacemaker. 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