{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T19:50:21Z","timestamp":1791316221911,"version":"4.3.1"},"reference-count":33,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T00:00:00Z","timestamp":1693785600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Conduction system pacing (CSP), including His\u2010bundle pacing (HBP) and left bundle branch area pacing (LBBAP), have been proposed as alternatives to biventricular pacing (BVP) in patients scheduled for ablate and pace (A&amp;P) strategy. The aim of this study was to compare the clinical outcomes, including the rate and nature of device\u2010related complications, between BVP and CSP in a cohort of patients undergoing A&amp;P.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Prospective, multicenter, observational study, enrolling consecutive patients undergoing A&amp;P. The risk of device\u2010related complications and of heart failure (HF) hospitalization was prospectively assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 373 patients (75.3\u00a0\u00b1\u00a08.7\u00a0years, 53.9% male, 68.9% with NYHA class \u2265III) were enrolled: 263 with BVP, 68 with HBP, and 42 with LBBAP. Baseline characteristics of the three groups were similar. Compared to BVP and HBP, LBBAP was associated with the shortest mean procedural and fluoroscopy times and with the lowest acute capture thresholds (all <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05). At 12\u2010month follow\u2010up LBBAP maintained the lowest capture thresholds and showed the longest estimated residual battery longevity (all <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05). At 12\u2010months follow\u2010up the three study groups showed a similar risk of device\u2010related complications (5.7%, 4.4%, and 2.4% for BVP, HBP, and LBBAP, respectively; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.650), and of HF hospitalization (2.7%, 1.5%, and 2.4% for BVP, HBP, and LBBAP, respectively; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.850).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In the setting of A&amp;P, CSP is a feasible pacing modality, with a midterm safety profile comparable to BVP. LBBAP offers the advantage of reducing procedural times and obtaining lower and stable capture thresholds, with a positive impact on the device longevity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.14813","type":"journal-article","created":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T10:09:51Z","timestamp":1693822191000},"page":"1258-1268","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Ablate and pace: Comparison of outcomes between conduction system pacing and biventricular pacing"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6705-6218","authenticated-orcid":false,"given":"Pietro","family":"Palmisano","sequence":"first","affiliation":[{"name":"Cardiology Unit, \u201cCard. G. 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Orsola\u2010Malpighi University Hospital  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Dell'Era","sequence":"additional","affiliation":[{"name":"Division of Cardiology University of Eastern Piedmont, Maggiore della Carit\u00e0 Hospital  Novara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Donateo","sequence":"additional","affiliation":[{"name":"Department of Cardiology Arrhythmology Center  Lavagna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernesto","family":"Ammendola","sequence":"additional","affiliation":[{"name":"Department of Cardiology Monaldi Hospital, Second University of Naples  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vittorio","family":"Aspromonte","sequence":"additional","affiliation":[{"name":"Cardiology\u2010Coronary Care Unit Pugliese\u2010Ciaccio Hospital  Catanzaro Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pier Lugi","family":"Pellegrino","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Policlinico Riuniti University Hospital  Foggia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Del Giorno","sequence":"additional","affiliation":[{"name":"Cardiology Unit \u201cMaria Ss Addolorata\u201d Hospital  Eboli Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Coluccia","sequence":"additional","affiliation":[{"name":"Cardiology Unit, \u201cCard. 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