{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T16:43:45Z","timestamp":1789663425394,"version":"4.0.1"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T00:00:00Z","timestamp":1701043200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Subcutaneous implantable cardioverter defibrillators (S\u2010ICDs) are occasionally used in combination with other cardiac implantable electronic devices (CIEDs). However, whether the incidence of inappropriate shock increases in patients with S\u2010ICDs and concomitant CIEDs remains unclear. This study aimed to investigate the association between the concomitant use of CIEDs and the incidence of inappropriate shock in patients with current\u2010generation S\u2010ICDs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 127 consecutive patients received an S\u2010ICD. Patients were assigned to two groups depending on concomitant use of CIEDs at the time of S\u2010ICD implantation: patients without other CIEDs (non\u2010combined group, 106 patients) and patients with other CIEDs (combined group, 21 patients). CIEDs included pacemakers, implantable cardioverter defibrillators, cardiac resynchronization therapy pacemakers, and cardiac resynchronization therapy defibrillators. The primary outcome was inappropriate shock, defined as a shock other than ventricular arrhythmia. Hazard ratios and 95% confidence intervals were calculated using a time\u2010varying Cox proportional hazards model which was adjusted for age because age differed between the groups and could be a confounder.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During a median follow\u2010up period of 2.2 years (interquartile range, 1.0\u20133.4 years), inappropriate shock events occurred in 17 (16%) and five (19%) patients of the non\u2010combined and combined groups, respectively. While the age\u2010adjusted hazard ratio for inappropriate shock was 24% higher in the combined than in the non\u2010combined group (hazard ratio\u00a0=\u00a01.24, 95% confidence interval, 0.39\u20133.97), this difference was insignificant (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.71).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The incidence of inappropriate shock did not differ between patients with and without concomitant use of CIEDs, suggesting that S\u2010ICDs could potentially be combined with other CIEDs without increasing the number of inappropriate shocks. Further studies are warranted to confirm the safety and feasibility of concomitant use of S\u2010ICDs and CIEDs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.14887","type":"journal-article","created":{"date-parts":[[2023,11,28]],"date-time":"2023-11-28T01:07:50Z","timestamp":1701133670000},"page":"131-138","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Inappropriate shock incidence in patients with subcutaneous implantable cardioverter\u2010defibrillators with concomitant cardiac implantable electronic devices: A single\u2010center cohort study"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-1659-7791","authenticated-orcid":false,"given":"Makiko","family":"Okazaki","sequence":"first","affiliation":[{"name":"Department of Clinical Engineering Sakakibara Heart Institute  Fuchu\u2010shi Tokyo Japan"},{"name":"Department of Health Data Science Yokohama City University Graduate 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