{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T17:12:14Z","timestamp":1785345134604,"version":"3.55.0"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,12,6]],"date-time":"2023-12-06T00:00:00Z","timestamp":1701820800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Conventional right ventricle (RV) pacemaker stimulation has been associated with worse clinical outcomes in patients with cardiac amyloidosis (CA). Left bundle branch area pacing (LABPP) has been suggested as a promising alternative. We sought to assess the safety, feasibility, and outcomes of LABPP in patients with CA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively analyzed echocardiography and pacing parameters and clinical outcomes in 23 consecutive patients with CA and LBBAP implanted from June 2020 to October 2022.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>LBBAP was successfully performed in 22 over 23 patients (19 male, 78.6\u00a0\u00b1\u00a011.7 years, 20 ATTR, mean LVEF 45.5\u00a0\u00b1\u00a016.2%). After the procedure, 9 patients showed Qr pattern and 11 a qR pattern in V1 on ECG. Average procedure time was 67\u00a0\u00b1\u00a028\u00a0min. After 7.7\u00a0\u00b1\u00a05.2 months follow\u2010up, no procedure\u2010related complications had occurred. Although, a significant reduction in QRS width (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.001) was achieved, we did not observe significant changes in LVEF and Nt ProBNP at 6 months of follow\u2010up. Pacing parameters were stable during follow\u2010up: LBB capture threshold and R wave amplitude were 1.0\u00a0\u00b1\u00a0\u20090.5\u00a0V and 10.6\u00a0\u00b1\u00a06.0\u2009mV versus 0.8\u00a0\u00b1\u00a0\u20090.1\u00a0V, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.21 and 10.6\u00a0\u00b1\u00a05.1\u00a0mV (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.985) at follow up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>LBBAP is safe and feasible pacing technique for patients with CA. LBBAP is associated with significant narrowing of QRSd without worsening in LVEF and Nt\u2010proBNP.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.14894","type":"journal-article","created":{"date-parts":[[2023,12,7]],"date-time":"2023-12-07T02:20:34Z","timestamp":1701915634000},"page":"149-155","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Feasibility and safety of left bundle branch area pacing in cardiac amyloidosis. A single center experience"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5435-3990","authenticated-orcid":false,"given":"Chinh","family":"Pham\u2010Trung","sequence":"first","affiliation":[{"name":"Electrophysiology Unit Cardiology Service. Hospital Universitario Puerta de Hierro  Majadahonda Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darwin","family":"Veloza\u2010Urrea","sequence":"additional","affiliation":[{"name":"Electrophysiology Unit Cardiology Service. Hospital Universitario Puerta de Hierro  Majadahonda Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melodie","family":"Segura\u2010Dom\u00ednguez","sequence":"additional","affiliation":[{"name":"Electrophysiology Unit Cardiology Service. Hospital Universitario Puerta de Hierro  Majadahonda Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuleisy","family":"De la Rosa Rojas","sequence":"additional","affiliation":[{"name":"Electrophysiology Unit Cardiology Service. Hospital Universitario Puerta de Hierro  Majadahonda Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Aguilera\u2010Agudo","sequence":"additional","affiliation":[{"name":"Electrophysiology Unit Cardiology Service. Hospital Universitario Puerta de Hierro  Majadahonda Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eusebio Alejandro","family":"Garc\u00eda\u2010Izquierdo","sequence":"additional","affiliation":[{"name":"Electrophysiology Unit Cardiology Service. Hospital Universitario Puerta de Hierro  Majadahonda Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Garc\u00eda\u2010Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Electrophysiology Unit Cardiology Service. Hospital Universitario Puerta de Hierro  Majadahonda Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5511-6954","authenticated-orcid":false,"given":"Diego","family":"Jim\u00e9nez\u2010S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Electrophysiology Unit Cardiology Service. Hospital Universitario Puerta de Hierro  Majadahonda Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alvaro","family":"Lorente\u2010Ros","sequence":"additional","affiliation":[{"name":"Electrophysiology Unit Cardiology Service. Hospital Universitario Puerta de Hierro  Majadahonda Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susana","family":"Mingo\u2010Santos","sequence":"additional","affiliation":[{"name":"Cardiac imaging Unit Cardiology Service. Hospital universitario Puerta de Hierro  Majadahonda Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Gonzalez\u2010Lopez","sequence":"additional","affiliation":[{"name":"Heart Failure and Inherited Cardiac Diseases Unit Department of Cardiology Hospital Universitario Puerta de Hierro Majadahonda IDIPHISA, CIBERCV  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Dom\u00ednguez","sequence":"additional","affiliation":[{"name":"Heart Failure and Inherited Cardiac Diseases Unit Department of Cardiology Hospital Universitario Puerta de Hierro Majadahonda IDIPHISA, CIBERCV  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Garcia\u2010Pavia","sequence":"additional","affiliation":[{"name":"Heart Failure and Inherited Cardiac Diseases Unit Department of Cardiology Hospital Universitario Puerta de Hierro Majadahonda IDIPHISA, CIBERCV  Madrid Spain"},{"name":"Centro Nacional de Investigaciones Cardiovasculares (CNIC)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Toquero\u2010Ramos","sequence":"additional","affiliation":[{"name":"Electrophysiology Unit Cardiology Service. 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