{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T23:04:55Z","timestamp":1793747095306,"version":"4.6.1"},"reference-count":19,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T00:00:00Z","timestamp":1718841600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T00:00:00Z","timestamp":1718841600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Tachycardia\u2010induced cardiomyopathy (TIC) is a reversible cardiomyopathy with ventricular dysfunction caused by tachyarrhythmias. Notably, atrial fibrillation (AF) is the most common causal arrhythmia leading to TIC. However, the risk factors for the development of TIC due to AF remain unclear. This study aimed to identify the associated factors of TIC due to AF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Persistent AF patients with heart rate (HR) \u2265100 beats per minute who underwent initial catheter ablation were enrolled in this study. TIC was diagnosed as left ventricular ejection fraction (LVEF)\u00a0&lt;\u00a050% during AF rhythm, which was recovered after the restoration of sinus rhythm. Non\u2010TIC was defined as LVEF \u2265 50% despite AF rhythm. The patient backgrounds were compared between the TIC group and the non\u2010TIC group to reveal the contributing factors of TIC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The TIC group comprised 57 patients, while the non\u2010TIC group consisted of 101 patients. The TIC group was younger than the non\u2010TIC group (median 64\u00a0vs. 70,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.006). Male sex was more frequent in the TIC group than the non\u2010TIC group (82.5%\u00a0vs. 58.4%,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.003). HR was higher in the TIC group than in the non\u2010TIC group (median 130\u00a0bpm vs. 111\u00a0bpm,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001). The number of smokers was significantly higher in the TIC group than in the non\u2010TIC group (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001). Multivariable analysis demonstrated that higher HR (odds ratio [OR]: 1.74; 95% confidence interval [CI]: 1.37\u20132.21;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001) and current smokers (OR: 5.27; 95% CI: 1.60\u201317.4;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.006) were the independent factors leading to TIC.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Higher HR and current smokers were independent risk factors for the development of TIC due to AF.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pace.15026","type":"journal-article","created":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T01:43:42Z","timestamp":1718934222000},"page":"1073-1078","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Risk factors for tachycardia\u2010induced cardiomyopathy due to atrial fibrillation"],"prefix":"10.1111","volume":"47","author":[{"given":"Koji","family":"Yasumoto","sequence":"first","affiliation":[{"name":"Division of Cardiology Osaka Rosai Hospital  Sakai Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuyuki","family":"Egami","sequence":"additional","affiliation":[{"name":"Division of Cardiology Osaka Rosai Hospital  Sakai Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Nohara","sequence":"additional","affiliation":[{"name":"Division of Cardiology Osaka Rosai Hospital  Sakai Osaka 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