{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T00:18:26Z","timestamp":1776298706700,"version":"3.50.1"},"reference-count":7,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,7,22]],"date-time":"2024-07-22T00:00:00Z","timestamp":1721606400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Electrical storm (ES) is among the most fearsome events in patients in waiting list for heart transplantation (HT) and catheter ablation (CA) demonstrated to be effective in reduce the arrhythmic burden. However, selection criteria for CA suitability in this specific population have never been addressed before. We retrospectively enrolled 36 patients (mean age 51\u00a0\u00b1\u00a08 years; 83% men) waiting HT referred to our department for ES resistant to antiarrhythmic drugs and percutaneous stellate ganglion blockade. Twenty patients were judged suitable for VT ablation according to specific criteria including absence of increased arrhythmic burden secondary to volume overload and hemodynamic decompensation; expected CA outcome favorable due to etiology of the cardiomyopathy, no need for coronary revascularization and technical feasibility of the procedure. The pre\u2010emptive use of mechanical circulatory supports (MCS) were discussed integrating the PAINESD score with additional clinical and hemodynamic parameters. Acute procedural success was accounted in 85% of cases with only two major complications. The CA group reported lower length of in\u2010hospital stay after CA suitability evaluation (56\u00a0\u00b1\u00a017\u00a0vs. 131\u00a0\u00b1\u00a064 days, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.004). Furthermore, at a mean follow\u2010up of 703\u00a0\u00b1\u00a0145 days, this group showed reduction of ventricular arrhythmia (VA) recurrence leading to implantable cardioverter defibrillator shock (4\u00a0vs. 8, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.051) and underwent HT with a lower level of urgency (0\u00a0vs. 6 patients needed for UNOS1 status upgrade). Respectively, one patient of the CA group and two patients of the conservative group died (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.839). At the end of follow\u2010up, eight patients underwent heart transplantation (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.964) while four patients underwent Left Ventricular Assist device (LVAD) implantation (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.440). This pilot study should be a proof for further studies exploring CA of VAs as a possible bridge therapy to HT.<\/jats:p>","DOI":"10.1111\/pace.15036","type":"journal-article","created":{"date-parts":[[2024,7,22]],"date-time":"2024-07-22T12:40:17Z","timestamp":1721652017000},"page":"1418-1422","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Exploring suitability to electrical storm ablation in patients in waiting list for heart transplantation: A single center experience"],"prefix":"10.1111","volume":"47","author":[{"given":"Lorenzo","family":"Gigli","sequence":"first","affiliation":[{"name":"Electrophysiology Unit De Gasperis Cardio Center Niguarda Hospital  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1584-5172","authenticated-orcid":false,"given":"Alberto","family":"Preda","sequence":"additional","affiliation":[{"name":"Electrophysiology Unit De Gasperis Cardio Center Niguarda Hospital  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marisa","family":"Varrenti","sequence":"additional","affiliation":[{"name":"Electrophysiology Unit De Gasperis Cardio Center Niguarda Hospital  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matteo","family":"Baroni","sequence":"additional","affiliation":[{"name":"Electrophysiology Unit De Gasperis Cardio Center Niguarda Hospital  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Vargiu","sequence":"additional","affiliation":[{"name":"Electrophysiology Unit De Gasperis Cardio Center Niguarda Hospital  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabrizio","family":"Guarracini","sequence":"additional","affiliation":[{"name":"Electrophysiology Unit De Gasperis Cardio Center Niguarda Hospital  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrico","family":"Ammirati","sequence":"additional","affiliation":[{"name":"De Gasperis Cardio Center Transplant Center Niguarda Hospital  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrizio","family":"Mazzone","sequence":"additional","affiliation":[{"name":"Electrophysiology Unit De Gasperis Cardio Center Niguarda Hospital  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,7,22]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.01.034"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2017.11.077"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.2333"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2022.08.037"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.000872"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.2645"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.121.009853"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.15036","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,9]],"date-time":"2024-10-09T06:06:34Z","timestamp":1728453994000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pace.15036"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,22]]},"references-count":7,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["10.1111\/pace.15036"],"URL":"https:\/\/doi.org\/10.1111\/pace.15036","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"value":"0147-8389","type":"print"},{"value":"1540-8159","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,22]]},"assertion":[{"value":"2024-01-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}