{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,12,11]],"date-time":"2024-12-11T05:44:43Z","timestamp":1733895883903,"version":"3.30.1"},"reference-count":25,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T00:00:00Z","timestamp":1729555200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The study aims to assess cardiac synchrony under different left bundle branch area pacing (LBBAP) and evaluate the relationship between different surface or intracardiac electrical parameters and mechanical synchrony.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eighty\u2010two patients with successful LBBAP were recruited. The electrical synchrony, evaluated by paced QRS duration (pQRSD) and Stim\u2010LVAT (stimulus to left ventricular activation time), and mechanical synchrony, evaluated by the\u00a0standard deviation of the time\u2010to\u2010peak contraction velocity in 12 left ventricular segments (Tsd\u201012\u2010LV), were compared between groups in patients underwent LBBAP. To investigate the relationship between different electrical parameters with mechanical synchrony under LBBAP, patients were divided into subgroups according to left ventricular activation time (LVAT, &lt; 60, 60\u201370, and &gt; 70\u00a0ms), presence of left bundle branch (LBB) potential (positive, negative), QRS axis (normal, left axis deviation [LAD]), and potential to ventricular interval (PVI, &lt; 20 and &gt; 20\u00a0ms). Mechanical synchrony was compared among the subgroups respectively 3 days post LBBAP procedure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No statistically significant differences were documented in electrical synchrony, evaluated by pQRSD, and mechanical synchrony, evaluated by Tsd\u201012\u2010LV among the subgroups divided by the stim\u2010LVAT, LBB potential, PVI duration, or paced QRS axis in the LBBAP group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>LBB potential, PVI, or normal paced QRS axis is not the prerequisite for successful LBBAP and optimal cardiac synchrony. Adopting a Stim\u2010LVAT value of less than 75\u00a0ms to attain ideal electrical and mechanical synchrony during the\u00a0LBBAP procedure may be applicable.<\/jats:p><\/jats:sec><jats:sec><jats:title>Trial registration<\/jats:title><jats:p><jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.chictr.org.cn\/index.aspx\">http:\/\/www.chictr.org.cn\/index.aspx<\/jats:ext-link>. ClinicalTrials.gov identifier: ChiCTR1800021104<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.15095","type":"journal-article","created":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T19:04:31Z","timestamp":1729623871000},"page":"1679-1687","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Relationship Between Electrical Parameters and Cardiac Synchrony in Patients Underwent Left Bundle Branch Area Pacing"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5406-9711","authenticated-orcid":false,"given":"Manxin","family":"Lin","sequence":"first","affiliation":[{"name":"Division of Cardiology Xiamen Cardiovascular Hospital Xiamen University  Xiamen Fujian China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shufen","family":"Huang","sequence":"additional","affiliation":[{"name":"Division of Cardiology Xiamen Cardiovascular Hospital Xiamen University  Xiamen Fujian China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinyi","family":"Huang","sequence":"additional","affiliation":[{"name":"Division of Echocardiography Xiamen Cardiovascular Hospital Xiamen University Xiamen Fujian China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7120-2203","authenticated-orcid":false,"given":"Jincun","family":"Guo","sequence":"additional","affiliation":[{"name":"Division of Cardiology Xiamen Cardiovascular Hospital Xiamen University  Xiamen Fujian China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linlin","family":"Li","sequence":"additional","affiliation":[{"name":"Division of Cardiology Xiamen Cardiovascular Hospital Xiamen University  Xiamen Fujian China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simei","family":"Chen","sequence":"additional","affiliation":[{"name":"Division of Cardiac Function Xiamen Cardiovascular Hospital Xiamen University Xiamen Fujian China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guiyang","family":"Li","sequence":"additional","affiliation":[{"name":"Division of Cardiology Xiamen Cardiovascular Hospital Xiamen University  Xiamen Fujian China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8353-374X","authenticated-orcid":false,"given":"Qiang","family":"Li","sequence":"additional","affiliation":[{"name":"Division of Cardiology Xiamen Cardiovascular Hospital Xiamen University  Xiamen Fujian China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong","family":"Chang","sequence":"additional","affiliation":[{"name":"Division of Cardiology Xiamen Cardiovascular Hospital Xiamen University  Xiamen Fujian China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maolong","family":"Su","sequence":"additional","affiliation":[{"name":"Division of Echocardiography Xiamen Cardiovascular Hospital Xiamen University Xiamen Fujian China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Binni","family":"Cai","sequence":"additional","affiliation":[{"name":"Division of Cardiology Xiamen Cardiovascular Hospital Xiamen University  Xiamen Fujian China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,10,22]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/clc.20677"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.12681"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540\u20108167.2010.01804.x"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540\u20108159.2006.00493.x"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr118"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl\u20102018\u2010313415"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2017.09.013"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.10.039"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euz188"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.14342"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eux120"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840\u2010014\u20109950\u20107"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.11.041"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.14190"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrcr.2019.01.006"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2019.09.006"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euy252"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2019.05.011"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2019.06.016"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/anec.12323"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12350\u2010020\u201002111\u20106"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.13956"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.14463"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euad043"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.15095","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T19:43:19Z","timestamp":1733859799000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pace.15095"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,22]]},"references-count":25,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1111\/pace.15095"],"URL":"https:\/\/doi.org\/10.1111\/pace.15095","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"type":"print","value":"0147-8389"},{"type":"electronic","value":"1540-8159"}],"subject":[],"published":{"date-parts":[[2024,10,22]]},"assertion":[{"value":"2024-02-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}