{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T23:45:16Z","timestamp":1773099916598,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T00:00:00Z","timestamp":1732665600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The effectiveness of cryoballoon ablation (CBA) of the left atrial (LA) roof in addition to pulmonary vein isolation (PVI) using a novel cryoballoon catheter, POLARx, remains unclear.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study compared the efficacy of LA roof line ablation and PVI using POLARx (Boston Scientific) or AFA\u2010Pro (Medtronic) in 100 patients with persistent atrial fibrillation. The right superior pulmonary vein (PV) anchoring and raise\u2010up techniques were consistently used for LA roof line ablation, and rapid right ventricular pacing was applied if the cryoballoon temperature did not reach \u221240\u00b0C.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Complete conduction block at the LA roof could be obtained in all patients with POLARx and in 98.0% of patients with AFA\u2010Pro. Rapid right ventricular pacing was needed in 64.0% of patients with AFA\u2010Pro and in no patients with POLARx. During LA roof line ablation, the nadir cryoballoon temperature was significantly lower with POLARx than with AFA\u2010Pro (right: \u221254.2\u00b0C\u00a0\u00b1\u00a04.4\u00b0C vs. \u221246.0\u00b0C\u00a0\u00b1\u00a05.4\u00b0C; central: \u221256.8\u00b0C\u00a0\u00b1\u00a04.4\u00b0C vs. \u221245.7\u00b0C\u00a0\u00b1\u00a04.8\u00b0C; left: \u221256.1\u00b0C\u00a0\u00b1\u00a04.3\u00b0C vs. \u221246.1\u00b0C\u00a0\u00b1\u00a05.7\u00b0C), and the cryoballoon temperature reached \u221240\u00b0C earlier with POLARx than with AFA\u2010Pro (right: 30.8\u00a0\u00b1\u00a07.4 s vs. 74.1\u00a0\u00b1\u00a037.7 s; central: 28.2\u00a0\u00b1\u00a05.2 s vs. 62.9\u00a0\u00b1\u00a030.9 s; left: 29.8\u00a0\u00b1\u00a05.8 s vs. 69.6\u00a0\u00b1\u00a040.7 s).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The nadir cryoballoon temperature with POLARx was approximately 10\u00b0C lower than with AFA\u2010Pro, consistently dropping below \u221240\u00b0C during LA roof line CBA. Thus, a complete conduction block of the LA roof line can be easily accomplished using right superior PV anchoring and the raise\u2010up techniques without the need for rapid right ventricular pacing with POLARx.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pace.15112","type":"journal-article","created":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T02:39:38Z","timestamp":1732761578000},"page":"119-127","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Comparative Study of Arctic Front Advance Pro and POLARx Cryoballoons for Linear Ablation of the Left Atrial Roof"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1781-9218","authenticated-orcid":false,"given":"Takatoshi","family":"Shigeta","sequence":"first","affiliation":[{"name":"Heart Center Japan Red Cross Yokohama City Bay Hospital  Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2588-3757","authenticated-orcid":false,"given":"Yuichiro","family":"Sagawa","sequence":"additional","affiliation":[{"name":"Heart Center Japan Red Cross Yokohama City Bay Hospital  Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9343-4614","authenticated-orcid":false,"given":"Hirofumi","family":"Arai","sequence":"additional","affiliation":[{"name":"Heart Center Japan Red Cross Yokohama City Bay Hospital  Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsuhito","family":"Oda","sequence":"additional","affiliation":[{"name":"Heart Center Japan Red Cross Yokohama City Bay Hospital  Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2445-7008","authenticated-orcid":false,"given":"Koji","family":"Sudo","sequence":"additional","affiliation":[{"name":"Heart Center Japan Red Cross Yokohama City Bay Hospital  Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2315-2923","authenticated-orcid":false,"given":"Kazuya","family":"Murata","sequence":"additional","affiliation":[{"name":"Heart Center Japan Red Cross Yokohama City Bay Hospital  Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8202-9442","authenticated-orcid":false,"given":"Kaoru","family":"Okishige","sequence":"additional","affiliation":[{"name":"Heart Center Japan Red Cross Yokohama City Bay Hospital  Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manabu","family":"Kurabayashi","sequence":"additional","affiliation":[{"name":"Heart Center Japan Red Cross Yokohama City Bay Hospital  Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7210-0671","authenticated-orcid":false,"given":"Masahiko","family":"Goya","sequence":"additional","affiliation":[{"name":"Arrhythmia Center International University of Health and Welfare Mita Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3582-6104","authenticated-orcid":false,"given":"Tetsuo","family":"Sasano","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Tokyo Medical and Dental University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4661-2999","authenticated-orcid":false,"given":"Yasuteru","family":"Yamauchi","sequence":"additional","affiliation":[{"name":"Heart Center Japan Red Cross Yokohama City Bay Hospital  Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,11,27]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1602014"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.14915"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.14930"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-21-0094"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-021-01035-6"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.14951"},{"key":"e_1_2_13_8_1","first-page":"1109","article-title":"Cryoballoon Ablation of Persistent Atrial Fibrillation: Feasibility and Safety of Left Atrial Roof Ablation With Generation of Conduction Block in Addition to Antral Pulmonary Vein Isolation","volume":"19","author":"Kuniss M.","year":"2017","journal-title":"Europace"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw210"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.16267"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-019-00641-9"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-019-01560-5"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.13879"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.14281"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2018.05.014"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euac005"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.14345"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/joa3.12654"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.14495"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/openhrt-2023-002426"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-022-01411-w"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00392\u2010024\u201002398\u20102"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.14387"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2020.11.016"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2017.01.028"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.15112","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T02:57:31Z","timestamp":1741748251000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pace.15112"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,27]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1111\/pace.15112"],"URL":"https:\/\/doi.org\/10.1111\/pace.15112","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"value":"0147-8389","type":"print"},{"value":"1540-8159","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,27]]},"assertion":[{"value":"2024-06-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}