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We present the case of a 59\u2010year\u2010old female patient with Down syndrome (DS) implanted with a dual\u2010chamber endovascular pacemaker due to symptomatic sinus node disfunction, reporting several syncopal episodes in last days and showing abnormal electrical parameters at the 2\u2010months follow\u2010up due to RS. The malfunctioning device was removed and an endocardial leadless pacing system was implanted.<\/jats:p>","DOI":"10.1111\/pace.15131","type":"journal-article","created":{"date-parts":[[2024,12,28]],"date-time":"2024-12-28T16:14:21Z","timestamp":1735402461000},"page":"235-238","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Managing a Mental Disorder With New Technologies: TheLeadless Pacemaker in Reel's Syndrome, a Case Report"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4370-891X","authenticated-orcid":false,"given":"P. 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