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We reported a case of a 63\u2010year\u2010old male who complained of progressive dyspnea after tislelizumab, a novel humanized anti\u2010PD\u20101 monoclonal antibody, for hepatocellular carcinoma. Upon diagnosing ICI\u2010related myocarditis, corticosteroid therapy was initiated immediately. The elevated biomarkers quickly decreased, but the atrioventricular block progressed from first\u2010degree to third\u2010degree, necessitating pacemaker implantation. This is the first report of complete AVB consecutive to tislelizumab\u2010induced myocarditis, highlighting the importance of early corticosteroid therapy and continuous electrocardiography monitoring.<\/jats:p>","DOI":"10.1111\/pace.15155","type":"journal-article","created":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T16:09:23Z","timestamp":1738858163000},"page":"414-417","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Progressed Atrioventricular Block in Immune Checkpoint Inhibitor Induced Myocarditis: A Case Report"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-4886-2944","authenticated-orcid":false,"given":"Dongmei","family":"Xie","sequence":"first","affiliation":[{"name":"Department of Cardiology West China Hospital Sichuan University  Chengdu China"},{"name":"West China School of Nursing Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ting","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Cardiology West China Hospital Sichuan University  Chengdu China"},{"name":"West China School of Nursing Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Cardiology West China Hospital Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingbin","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Cardiology West China Hospital Sichuan University  Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,6]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-020-01286-z"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/jitc-2021-002553"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/1759-7714.13250"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(18)30608-9"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)30533-6"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.02.037"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2021.2241"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.799077"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000031873"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.1053370"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(18)30608-9"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2020.00557"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1609214"},{"issue":"1","key":"e_1_2_10_15_1","first-page":"34","article-title":"Complete Heart Block Is a Significant Predictor of Mortality in Immune Checkpoint Inhibitor Myocarditis","volume":"9","author":"O'Shea M. 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