{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T16:51:18Z","timestamp":1790009478766,"version":"4.0.1"},"reference-count":75,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,6,15]],"date-time":"2025-06-15T00:00:00Z","timestamp":1749945600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,6,15]],"date-time":"2025-06-15T00:00:00Z","timestamp":1749945600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Left bundle branch area pacing (LBBAP) is an emerging technique in conduction system pacing (CSP) that may offer improved outcomes over traditional methods. Typically, lumenless leads are used; however, stylet\u2010driven leads have recently been considered. This study conducts a systematic review and meta\u2010analysis evaluating the efficacy and complications of stylet\u2010driven leads versus lumenless leads.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>Databases including PubMed, Embase, and Scopus were searched from inception to June 2024 for relevant studies. We included published prospective or retrospective randomized controlled trials and cohort studies using stylet\u2010driven leads or lumenless leads for LBBAP. Data were combined using a random\u2010effects, generic inverse variance method of DerSimonian and Laird.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Sixty\u2010eight studies involving 8996 patients from 2016 to 2023 were included. From eight head\u2010to\u2010head studies, the stylet\u2010driven leads group had a comparable success rate (OR = 1.46, 95% CI: 0.89, 2.39) but showed shorter procedural time (weighted mean difference [WMD] = \u221216.82 min, 95% CI: \u221224.42, \u22129.21). Stylet\u2010driven leads had a higher pacing threshold at implantation (WMD = 0.09\u00a0V, 95% CI: 0.00, 0.17) and lower lead impedance (WMD = \u221286.13 ohms, 95% CI: \u2212129.46, \u221242.80). QRS duration and R wave amplitude were comparable initially, but at follow\u2010up (1\u201312 months), stylet\u2010driven leads had a lower R wave amplitude (WMD = \u22121.92\u00a0mV, 95% CI: \u22123.33, \u22120.51). Complication rates were higher with stylet\u2010driven leads (OR = 1.80, 95% CI: 1.34, 2.41), particularly lead dislodgement (OR = 3.26, 95% CI: 1.75, 6.07) and helix damage (OR = 11.46, 95% CI: 3.58, 36.63).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this meta\u2010analysis of 8996 patients, stylet\u2010driven leads for LBBAP showed a comparable success rate to lumenless leads but was associated with a higher complication risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pace.15217","type":"journal-article","created":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T01:40:52Z","timestamp":1750038052000},"page":"700-721","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Comparing Efficacy and Complications Between Stylet\u2010Driven Leads and Lumenless Leads in Left Bundle Branch Area Pacing"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-3338-1193","authenticated-orcid":false,"given":"Adivitch","family":"Sripusanapan","sequence":"first","affiliation":[{"name":"Faculty of Medicine Chiang Mai University  Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicha","family":"Wareesawetsuwan","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Siriraj Hospital Mahidol University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natee","family":"Deepan","sequence":"additional","affiliation":[{"name":"Chulalongkorn University, Division of Cardiology Department of Medicine  Bangkok Thailand"},{"name":"Division of Cardiovascular Medicine, Center of Excellence in Arrhythmia Research, Cardiac Center, King Chulalongkorn Memorial Hospital, Faculty of Medicine Chulalongkorn University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thanaboon","family":"Yinadsawaphan","sequence":"additional","affiliation":[{"name":"Internal Medicine Residency Program University of Hawaii, Honolulu  Hawaii USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2258-0598","authenticated-orcid":false,"given":"Dingxin","family":"Qin","sequence":"additional","affiliation":[{"name":"Cardiac Arrhythmia Service Massachusetts General Hospital Harvard University  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9419-5854","authenticated-orcid":false,"given":"Pattara","family":"Rattanawong","sequence":"additional","affiliation":[{"name":"Cardiac Arrhythmia Service Massachusetts General Hospital Harvard University  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chee 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