{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T00:01:06Z","timestamp":1773792066377,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T00:00:00Z","timestamp":1751932800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T00:00:00Z","timestamp":1751932800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Left bundle branch area pacing (LBBAP) is emerging as a physiological alternative to conventional pacing, particularly in elderly patients. Stylet\u2010driven leads (SDL) offer unique procedural advantages, but data on their safety and efficacy in octogenarians remain sparse.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study evaluates the feasibility, safety, and outcomes of SDL for LBBAP in octogenarians.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective, single\u2010center study included 117 octogenarian patients (\u226580 years) and 308 younger patients (&lt;80 years) who underwent LBBAP with SDL between May 2022 and December 2023. Baseline characteristics, procedural success, and follow\u2010up outcomes were analyzed. Complication rates and pacing parameters were assessed over 12 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Procedural success was high in both groups (93.2% in octogenarians vs. 96.1% in younger patients). Octogenarians had slightly longer fluoroscopy times (13.2\u00a0\u00b1\u00a01.4\u00a0vs. 11.8\u00a0\u00b1\u00a01.6 min,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.031) and higher pacing thresholds at implantation (1.03\u00a0\u00b1\u00a00.56\u00a0V vs. 0.82\u00a0\u00b1\u00a00.42\u00a0V,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.001). At 12 months, event\u2010free survival was 91.4% in octogenarians and 94.8% in younger patients (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.288). The overall complication rate was low (5.1%\u00a0vs. 3.6%,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.957), and no significant differences in pacing parameters were observed between groups. Improvements in left ventricular ejection fraction (LVEF) and QRS duration were consistent across both cohorts.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>SDLs are safe and effective for LBBAP in octogenarians, providing high procedural success and significant clinical improvements. These findings highlight the potential of SDL as a viable option for elderly patients requiring physiological pacing, addressing the unique challenges posed by advanced age.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pace.70010","type":"journal-article","created":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T04:05:13Z","timestamp":1751947513000},"page":"821-826","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Safety and Efficacy of Stylet\u2010Driven Leads for Left Bundle Branch Area Pacing in Octogenarians"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2672-5109","authenticated-orcid":false,"given":"Ahmet","family":"Korkmaz","sequence":"first","affiliation":[{"name":"Cardiology Department Ankara Bilkent City Hospital  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5969-2345","authenticated-orcid":false,"given":"Elif Hande","family":"Ozcan Cetin","sequence":"additional","affiliation":[{"name":"Cardiology Department Ankara Bilkent City Hospital  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koray","family":"Arslan","sequence":"additional","affiliation":[{"name":"Cardiology Department Ankara Bilkent City Hospital  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet Serkan","family":"Cetin","sequence":"additional","affiliation":[{"name":"Cardiology Department Ankara Bilkent City Hospital  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00fccahit","family":"G\u00f6l","sequence":"additional","affiliation":[{"name":"Cardiology Department Ankara Bilkent City Hospital  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9321-5673","authenticated-orcid":false,"given":"Hasan Can","family":"K\u00f6nte","sequence":"additional","affiliation":[{"name":"Cardiology Department Ankara Bilkent City Hospital  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meryem","family":"Kara","sequence":"additional","affiliation":[{"name":"Cardiology Department Ankara Bilkent City Hospital  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F\u0131rat","family":"Ozcan","sequence":"additional","affiliation":[{"name":"Cardiology Department Ankara Bilkent City Hospital  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4770-8159","authenticated-orcid":false,"given":"Ozcan","family":"Ozeke","sequence":"additional","affiliation":[{"name":"Cardiology Department Ankara Bilkent City Hospital  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5476-1214","authenticated-orcid":false,"given":"Serkan","family":"Cay","sequence":"additional","affiliation":[{"name":"Cardiology Department Ankara Bilkent City Hospital  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dursun","family":"Aras","sequence":"additional","affiliation":[{"name":"Cardiology Department Bah\u00e7elievler Medipol Hospital  \u0130stanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serkan","family":"Topaloglu","sequence":"additional","affiliation":[{"name":"Cardiology Department Ankara Bilkent City Hospital  Ankara 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