{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T07:52:54Z","timestamp":1773647574776,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T00:00:00Z","timestamp":1757980800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T00:00:00Z","timestamp":1757980800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Left bundle branch area pacing (LBBAP) has emerged as an alternative to cardiac stimulation via right ventricular pacing and cardiac resynchronization therapy using coronary sinus leads. The approach utilizes dedicated three\u2010dimensional guiding catheters for lead placement. Our objective was to evaluate the feasibility and safety of a simplified approach of implantation of an LBBAP electrode without a dedicated guiding catheter.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a prospective single\u2010center proof\u2010of\u2010concept evaluation. Patients with an indication for dual\u2010chamber pacemaker implantation were consecutively enrolled. All patients received ventricular lead placement with a commercially available stylet\u2010driven pacemaker lead. LBBAP was attempted without the use of a dedicated guiding catheter but with the help of a manually three\u2010dimensionally pre\u2010curved stylet.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 24 patients were analyzed. Procedure and fluoroscopy durations were 61\u00a0\u00b1\u00a012 min and 7.4\u00a0\u00b1\u00a03.9\u00a0min, while LBBAP lead placement was successful in 19 patients (79%). In these patients, the V6\u2010R\u2010wave peak time was 74\u00a0\u00b1\u00a011\u00a0ms, the V1V6 interpeak interval was 51\u00a0\u00b1\u00a011\u00a0ms, and QRS width during unipolar stimulation was 123\u00a0\u00b1\u00a014\u00a0ms. No complications attributed to the transseptal route of the pacing lead occurred. After a mean follow\u2010up of 104\u00a0\u00b1\u00a020 days, there was no significant change in QRS widths (123\u00a0\u00b1\u00a015\u00a0ms,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.94), V6\u2010R wave peak time (70\u00a0\u00b1\u00a011\u00a0ms,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.3), and V1V6 interpeak interval (45\u00a0\u00b1\u00a010\u00a0ms;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.12).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Implantation of an LBBAP electrode without the use of a dedicated three\u2010dimensional sheath is feasible and safe in a high proportion of patients. Further studies are necessary to define the impact of this technique for potential use in clinical routine.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pace.70039","type":"journal-article","created":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T09:50:53Z","timestamp":1758016253000},"page":"1086-1093","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Initial Experience With Implantation Left Bundle Branch Pacing Leads Without a Dedicated Three\u2010Dimensional Sheath"],"prefix":"10.1111","volume":"48","author":[{"given":"Cord\u2010Friedrich","family":"Niehaus","sequence":"first","affiliation":[{"name":"Clinic for Electrophysiology, Herz\u2010 und Diabeteszentrum NRW, Ruhr\u2010Universit\u00e4t Bochum, Bad Oeynhausen, Germany Herz\u2010 und Diabeteszentrum NRW Ruhr\u2010Universit\u00e4t Bochum Bad Oeynhausen Germany"},{"name":"Clinic For Internal Medicine\/Cardiology St. Marienhospital Vechta  Vechta Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guram","family":"Imnadze","sequence":"additional","affiliation":[{"name":"Clinic for Electrophysiology, Herz\u2010 und Diabeteszentrum NRW, Ruhr\u2010Universit\u00e4t Bochum, Bad Oeynhausen, Germany Herz\u2010 und Diabeteszentrum NRW Ruhr\u2010Universit\u00e4t Bochum Bad Oeynhausen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Eitz","sequence":"additional","affiliation":[{"name":"Clinic for Thoracic and Cardiovascular Surgery Herz \u2010und Diabeteszentrum NRW Ruhr\u2010Universit\u00e4t Bochum Bad Oeynhausen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heinrich","family":"Weglage","sequence":"additional","affiliation":[{"name":"Clinic For Internal Medicine\/Cardiology and Intensive Care Medicine Niels\u2010Stensen\u2010Kliniken Marienhospital Osnabr\u00fcck Osnabr\u00fcck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa","family":"Sciacca","sequence":"additional","affiliation":[{"name":"Clinic for Electrophysiology, Herz\u2010 und Diabeteszentrum NRW, Ruhr\u2010Universit\u00e4t Bochum, Bad Oeynhausen, Germany Herz\u2010 und Diabeteszentrum NRW Ruhr\u2010Universit\u00e4t Bochum Bad Oeynhausen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Lucas","sequence":"additional","affiliation":[{"name":"Clinic for Electrophysiology, Herz\u2010 und Diabeteszentrum NRW, Ruhr\u2010Universit\u00e4t Bochum, Bad Oeynhausen, Germany Herz\u2010 und Diabeteszentrum NRW Ruhr\u2010Universit\u00e4t Bochum Bad Oeynhausen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lilit","family":"Antonyan","sequence":"additional","affiliation":[{"name":"Clinic for Electrophysiology, Herz\u2010 und Diabeteszentrum NRW, Ruhr\u2010Universit\u00e4t Bochum, Bad Oeynhausen, Germany Herz\u2010 und Diabeteszentrum NRW Ruhr\u2010Universit\u00e4t Bochum Bad Oeynhausen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastian E.","family":"Beyer","sequence":"additional","affiliation":[{"name":"Clinic for Electrophysiology, Herz\u2010 und Diabeteszentrum NRW, Ruhr\u2010Universit\u00e4t Bochum, Bad Oeynhausen, Germany Herz\u2010 und Diabeteszentrum NRW Ruhr\u2010Universit\u00e4t Bochum Bad Oeynhausen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ersan","family":"Akkaya","sequence":"additional","affiliation":[{"name":"Clinic for Electrophysiology, Herz\u2010 und Diabeteszentrum NRW, Ruhr\u2010Universit\u00e4t Bochum, Bad Oeynhausen, Germany Herz\u2010 und Diabeteszentrum NRW Ruhr\u2010Universit\u00e4t Bochum Bad Oeynhausen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elias","family":"Waezsada","sequence":"additional","affiliation":[{"name":"Clinic for Electrophysiology, Herz\u2010 und Diabeteszentrum NRW, Ruhr\u2010Universit\u00e4t Bochum, Bad Oeynhausen, Germany Herz\u2010 und Diabeteszentrum NRW Ruhr\u2010Universit\u00e4t Bochum Bad Oeynhausen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuri","family":"Bocchini","sequence":"additional","affiliation":[{"name":"Clinic for Electrophysiology, Herz\u2010 und Diabeteszentrum NRW, Ruhr\u2010Universit\u00e4t Bochum, Bad Oeynhausen, Germany Herz\u2010 und Diabeteszentrum NRW Ruhr\u2010Universit\u00e4t Bochum Bad Oeynhausen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustapha El","family":"Hamriti","sequence":"additional","affiliation":[{"name":"Clinic for Electrophysiology, Herz\u2010 und Diabeteszentrum NRW, Ruhr\u2010Universit\u00e4t Bochum, Bad Oeynhausen, Germany Herz\u2010 und Diabeteszentrum NRW Ruhr\u2010Universit\u00e4t Bochum Bad Oeynhausen Germany"},{"name":"Clinic For Cardiology and Angiology GZO Spital Wetzikon  Wetzikon Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan","family":"Winnik","sequence":"additional","affiliation":[{"name":"Clinic for Electrophysiology, Herz\u2010 und Diabeteszentrum NRW, Ruhr\u2010Universit\u00e4t Bochum, Bad Oeynhausen, Germany Herz\u2010 und Diabeteszentrum NRW Ruhr\u2010Universit\u00e4t Bochum Bad Oeynhausen Germany"},{"name":"Clinic For Cardiology and Angiology GZO Spital Wetzikon  Wetzikon Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denise","family":"Guckel","sequence":"additional","affiliation":[{"name":"Clinic for Electrophysiology, Herz\u2010 und Diabeteszentrum NRW, Ruhr\u2010Universit\u00e4t Bochum, Bad Oeynhausen, Germany Herz\u2010 und Diabeteszentrum NRW Ruhr\u2010Universit\u00e4t Bochum Bad Oeynhausen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maxim","family":"Didenko","sequence":"additional","affiliation":[{"name":"Clinic for Electrophysiology, Herz\u2010 und Diabeteszentrum NRW, Ruhr\u2010Universit\u00e4t Bochum, Bad Oeynhausen, Germany Herz\u2010 und Diabeteszentrum NRW Ruhr\u2010Universit\u00e4t Bochum Bad Oeynhausen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moneeb","family":"Khalaph","sequence":"additional","affiliation":[{"name":"Clinic for Electrophysiology, Herz\u2010 und Diabeteszentrum NRW, Ruhr\u2010Universit\u00e4t Bochum, Bad Oeynhausen, Germany Herz\u2010 und Diabeteszentrum NRW Ruhr\u2010Universit\u00e4t Bochum Bad Oeynhausen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Sohns","sequence":"additional","affiliation":[{"name":"Clinic for Electrophysiology, Herz\u2010 und Diabeteszentrum NRW, Ruhr\u2010Universit\u00e4t Bochum, Bad Oeynhausen, Germany Herz\u2010 und Diabeteszentrum NRW Ruhr\u2010Universit\u00e4t Bochum Bad Oeynhausen 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