{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T02:19:18Z","timestamp":1778811558500,"version":"3.51.4"},"reference-count":15,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T00:00:00Z","timestamp":1758585600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T00:00:00Z","timestamp":1758585600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>A persistent left superior vena cava (PLSVC) can be a trigger for atrial fibrillation (AF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We aimed to compare post\u2010ablation 1\u2010year freedom from recurrent atrial tachycardia (AT)\/AF in PLSVC patients with a matched population without PLSVC (n\u2010PLSVC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A single\u2010center, retrospective, case\u2013control study between 2008 and 2022. Pre\u2010ablation imaging identified patients with PLSVC. Propensity score matching for age, sex, BMI, type of AF, AF ablation energy type, left atrial volume, and year of ablation was performed to identify five controls for each PLSVC patient. We excluded patients who had less than 1 year of follow\u2010up post\u2010ablation or underwent prior surgical ablation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There were 90 total patients including 15 PLSVC patients and 75 matched controls (60 \u00b1 10 years old, 31% women, 58% paroxysmal, 62% radiofrequency). One\u2010year freedom from AF was lower with PLSVC (27%) than n\u2010PLSVC (59%,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.02). The PLSVC was targeted for ablation in 5\/15 patients (33%), all of whom had recurrent AT\/AF within 1 year. Redo AF ablations were performed in 40% (6\/15) of PLSVC patients. Freedom from AF at last follow\u2010up (median 2.1, IQR 0.5\u20134.0 years) was 83% in PLSVC patients who underwent redo ablation. The only complication was right atrial lead dysfunction post\u2010ablation requiring lead revision.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Although the post\u2010ablation freedom from AF is lower in patients with PLSVC than n\u2010PLSVC, repeat ablation can result in a high freedom from AF in patients with PLSVC. Further study is necessary to determine the optimal methods and role for PLSVC ablation (including the role for pulse\u2010field ablation).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pace.70047","type":"journal-article","created":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T11:43:07Z","timestamp":1758627787000},"page":"1176-1183","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of Persistent Left Superior Vena Cava on Outcomes With Atrial Fibrillation Ablation"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-5233-5681","authenticated-orcid":false,"given":"Claire","family":"Sorensen","sequence":"first","affiliation":[{"name":"Department of Medical Education University of Kansas School of Medicine  Kansas City Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Shahab","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine The University of Kansas Medical Center  Kansas City Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinxiang","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Data Science University of Kansas School of Medicine  Kansas City Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raghu","family":"Dendi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine The University of Kansas Medical Center  Kansas City Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Emert","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine The University of Kansas Medical Center  Kansas City Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit","family":"Noheria","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine The University of Kansas Medical Center  Kansas City Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rhea","family":"Pimentel","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine The University of Kansas Medical Center  Kansas City Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rigoberto","family":"Ramirez","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine The University of Kansas Medical Center  Kansas City Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y. Madhu","family":"Reddy","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine The University of Kansas Medical Center  Kansas City Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0543-2040","authenticated-orcid":false,"given":"Seth H.","family":"Sheldon","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine The University of Kansas Medical Center  Kansas City Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,23]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i4482"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2021.03.032"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13244-020-00906-2"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000116753.56467.BC"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euz254"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2022.11.060"},{"issue":"2","key":"e_1_2_9_8_1","first-page":"1226","article-title":"Very Long\u2010Term Results of Atrial Fibrillation Ablation Confirm That this Therapy is Really Effective","volume":"8","author":"Tutuianu C.","year":"2015","journal-title":"Journal of Atrial Fibrillation"},{"issue":"5","key":"e_1_2_9_9_1","first-page":"590","article-title":"Second\u2010Generation Cryoballoon Atrial Fibrillation Ablation in Patients with Persistent Left Superior Caval Vein","volume":"5","author":"Santoro F.","year":"2019","journal-title":"J Am Coll Cardiol EP"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2010.08.005"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v042.i08"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.109.205419"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-018-0444-x"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.15900"},{"issue":"5","key":"e_1_2_9_15_1","first-page":"301","article-title":"Pulsed Field Ablation for Persistent Superior Vena Cava: New Solution for an Old Problem","volume":"4","author":"Tohoku S.","year":"2022","journal-title":"J Am Coll Cardiol Case Rep"},{"issue":"12","key":"e_1_2_9_16_1","first-page":"1618","article-title":"Coronary Spasm during Pulsed Field Ablation of the Mitral Isthmus Line","volume":"7","author":"Gunawardene M. A.","year":"2021","journal-title":"J Am Coll Cardiol EP"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.70047","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pace.70047","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.70047","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T07:08:13Z","timestamp":1773644893000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pace.70047"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,23]]},"references-count":15,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1111\/pace.70047"],"URL":"https:\/\/doi.org\/10.1111\/pace.70047","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"value":"0147-8389","type":"print"},{"value":"1540-8159","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,23]]},"assertion":[{"value":"2024-11-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}