{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T20:03:31Z","timestamp":1783973011514,"version":"3.55.0"},"reference-count":10,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:00:00Z","timestamp":1761177600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The benefit of oral anticoagulation (OAC) in patients with new\u2010onset postoperative atrial fibrillation (POAF) after coronary bypass grafting remains uncertain. The 2023 American Heart Association (AHA) and the American College of Cardiology (ACC) guidelines recommend 60 days of anticoagulation for POAF, whereas management was previously left to the physician's discretion. The aim of this study is to identify the most effective anticoagulant regimens for reducing stroke rates in POAF patients after coronary artery bypass grafting (CABG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Using the Epic Cosmos database, we included all US patients who underwent CABG without concomitant aortic\/mitral valve replacement (MVR) from 2017 to 2023. Primary outcomes include demographics of POAF\/non\u2010POAF patients and complication rates among patients without anticoagulation, on direct oral anticoagulation (DOAC), or on warfarin.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 147,546 patients studied, 7.6% (11,336) developed POAF. At 60 days, the use of OAC for POAF was associated with a decrease in all\u2010cause mortality without any difference in thromboembolism rates. At 12 months, there was no difference between all\u2010cause mortality and thromboembolism rates between the OAC and the no anticoagulation (NA) cohorts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The benefit of long\u2010term anticoagulation of POAF following CABG with warfarin or DOAC remains unclear, as there was no reduction in thromboembolic events with anticoagulation despite a reduction in all\u2010cause mortality at 60 days. No significant reduction in thromboembolic events or all\u2010cause mortality was exhibited at 1\u00a0year. Thus, the benefit of long\u2010term anticoagulation of POAF following CABG with warfarin or DOAC remains unclear.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pace.70069","type":"journal-article","created":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T11:23:07Z","timestamp":1761218587000},"page":"1444-1450","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Trends and Outcomes of Anticoagulation for Post\u2010Operative Atrial Fibrillation After Coronary Artery Bypass Graft"],"prefix":"10.1111","volume":"48","author":[{"given":"Daniel S.","family":"Cheah","sequence":"first","affiliation":[{"name":"Carle Illinois College of Medicine  Urbana Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5825-9811","authenticated-orcid":false,"given":"Kathryn","family":"Tsai","sequence":"additional","affiliation":[{"name":"Carle Illinois College of Medicine  Urbana Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishna Prasad","family":"Kurpad","sequence":"additional","affiliation":[{"name":"Department of Cardiology Carle Foundation Hospital  Urbana Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yousra","family":"Khalid","sequence":"additional","affiliation":[{"name":"Department of Medicine West Virginia University  Morgantown West Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay S.","family":"Mehta","sequence":"additional","affiliation":[{"name":"Carle Illinois College of Medicine  Urbana Illinois USA"},{"name":"Department of Cardiology Carle Foundation Hospital  Urbana Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,23]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.12.012"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000040"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.017966"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.017559"},{"key":"e_1_2_10_6_1","article-title":"Anticoagulation for Post\u2010Operative Atrial Fibrillation After Isolated Coronary Artery Bypass Grafting: A Meta\u2010Analysis","author":"Kar M. R. D.","year":"2024","journal-title":"European Heart Journal"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.116.003023"},{"key":"e_1_2_10_8_1","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.124.035708","article-title":"Ten\u2010Year Trend of Oral Anticoagulation Use in Postoperative and Nonpostoperative Atrial Fibrillation in Routine Clinical Practice","volume":"13","author":"Yao X.","year":"2024","journal-title":"Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2303062"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2023.10.016"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.108.816843"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.70069","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T14:51:08Z","timestamp":1764687068000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pace.70069"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,23]]},"references-count":10,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.1111\/pace.70069"],"URL":"https:\/\/doi.org\/10.1111\/pace.70069","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"value":"0147-8389","type":"print"},{"value":"1540-8159","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,23]]},"assertion":[{"value":"2025-03-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}