{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:08:54Z","timestamp":1787843334954,"version":"build-2784847793"},"reference-count":36,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T00:00:00Z","timestamp":1770940800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T00:00:00Z","timestamp":1770940800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Effective pulmonary vein isolation (PVI) using cryoballoon (CB) ablation relies on adequate pulmonary vein (PV) occlusion, which may be influenced by PV and left atrial (LA) anatomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the impact of PV and LA anatomy, assessed by cardiac computed tomography (CT), on long\u2010term outcomes and complications following CB ablation for AF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective study included 416 patients (54.8% female, mean age 57.5 \u00b1 12.4 years) who underwent CB ablation for symptomatic AF. Paroxysmal AF was present in 87% and persistent AF in 13% of patients. Arctic Front Advance or Arctic Front Advance PRO catheters were used. All patients had preprocedural cardiac CT. AF recurrence and procedural complications were evaluated over a median follow\u2010up of 46.5 months (range: 6\u2013116).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Freedom from AF was observed in 73.1% of patients during follow\u2010up. Multivariable Cox regression analysis revealed that the maximum diameter of right superior PV (RSPV) (HR: 1.076, 95% CI: 1.003\u20131.154,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.040) and the frontal angle of the left superior PV (LSPV) (HR:0.984, 95% CI: 0.968\u20130.999,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.048) were independent predictors of recurrence. Independent predictors of phrenic nerve injury included the frontal angle of the RSPV (OR: 1.072, 95% CI: 1.020\u20131.126,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.006) and the distance between the RSPV and the right phrenic nerve bundle (OR: 0.327, 95% CI: 0.188\u20130.579,\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Specific PV anatomical features influence AF recurrence and PNI after CB ablation. Preprocedural cardiac CT may help tailor ablation strategies and optimize patient outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pace.70154","type":"journal-article","created":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T10:06:12Z","timestamp":1770977172000},"page":"778-788","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of Pulmonary Vein Anatomy on Outcomes in Patients Undergoing Cryoballoon Ablation for Atrial Fibrillation"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3332-9112","authenticated-orcid":false,"given":"Ahmet Haydar","family":"Keresteci","sequence":"first","affiliation":[{"name":"Department of Cardiology Faculty of Medicine Hacettepe University  Ankara Turkey"},{"name":"Department of Cardiology Sincan Training and Research Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5520-7103","authenticated-orcid":false,"given":"Cem","family":"\u00c7\u00f6teli","sequence":"additional","affiliation":[{"name":"Department of Cardiology Faculty of Medicine Hacettepe University  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet Hakan","family":"Ate\u015f","sequence":"additional","affiliation":[{"name":"Department of Cardiology Faculty of Medicine Hacettepe University  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selin","family":"Ardal\u0131 D\u00fczg\u00fcn","sequence":"additional","affiliation":[{"name":"Department of Radiology Faculty of Medicine Hacettepe University  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuncay","family":"Haz\u0131rolan","sequence":"additional","affiliation":[{"name":"Department of Radiology Faculty of Medicine Hacettepe University  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hikmet","family":"Yorgun","sequence":"additional","affiliation":[{"name":"Department of Cardiology Faculty of Medicine Hacettepe University  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kudret","family":"Aytemir","sequence":"additional","affiliation":[{"name":"Department of Cardiology Faculty of Medicine Hacettepe University  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,13]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.10.946"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euae043"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw285"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2018.11.006"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2307291"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000151289.73085.36"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/openhrt-2021-001724"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.12660"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-020-00799-7"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-023-01554-4"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eut155"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2016.01.009"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jeac255"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics12061322"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2010.03.027"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euu273"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euu078"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9103164"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eux013"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-43283-7"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2010.01984.x"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2015.10.033"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcct.2010.01.016"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(03)00124-4"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.12834"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.113.000758"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.121.010516"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euz155"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eux337"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euu320"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euae092"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2007.01.072"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.115.002725"},{"key":"e_1_2_11_35_1","first-page":"1314","article-title":"Comparison of Phrenic Nerve Injury During Atrial Fibrillation Ablation Between Different Modalities, Pathophysiology and Management","volume":"8","author":"Parikh V.","year":"2015","journal-title":"Journal of Atrial Fibrillation"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euae016"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.13047"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.70154","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pace.70154","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.70154","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T14:10:13Z","timestamp":1781532613000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pace.70154"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,13]]},"references-count":36,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1111\/pace.70154"],"URL":"https:\/\/doi.org\/10.1111\/pace.70154","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"value":"0147-8389","type":"print"},{"value":"1540-8159","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,13]]},"assertion":[{"value":"2025-08-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}