{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T12:08:32Z","timestamp":1784030912653,"version":"3.55.0"},"reference-count":34,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T00:00:00Z","timestamp":1771977600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T00:00:00Z","timestamp":1771977600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Cardiac amyloidosis can cause congestive heart failure, arrhythmias, and heart blocks, which frequently require cardiac device implantation (CDI). However, the differences between light chain (AL) amyloidosis and transthyretin (ATTR) amyloidosis CDI requirements are unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective analysis was conducted using the National Inpatient Sample 2017\u20132020 with respective ICD\u201010 codes. Weighted multivariate regression was used to analyze in\u2010hospital mortality by adjusting for confounders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 1,008,010 patients hospitalized for CDI, 160 patients had underlying AL\u2010AMD, while 200 patients had underlying ATTR\u2010AMD. Patients undergoing CDI with underlying ATTR\u2010AMD had a higher mean age (76.7 vs. 68.4\u00a0years,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.001), and a higher male proportion (80% vs. 46.8%,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.005) as compared to those with AL\u2010AMD. ATTR\u2010AMD had a higher CDI rate than AL\u2010AMD (1.4% vs. 8.3%). The predominant device implanted in both AL\u2010AMD and ATTR\u2010AMD was a permanent pacemaker (PPM) (0.8% vs. 5.7%). Underlying AL\u2010AMD was associated with higher in\u2010hospital mortality in patients undergoing PPM (OR 5.1, CI 1.3\u201319,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.01), and implantable\u2010cardioverter defibrillator (ICD) implantation (OR 21.5, CI 4.6\u201399,\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      &lt;\u00a00.001). Patients undergoing CDI with underlying AL\u2010AMD had a higher mean length of stay.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>ATTR\u2010AMD has a higher CDI rate as compared to AL\u2010AMD. Underlying AL\u2010AMD is associated with higher in\u2010hospital mortality in patients undergoing PP and ICD implantation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pace.70180","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T19:22:36Z","timestamp":1772997756000},"page":"954-961","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Utilization and Prognosis of Cardiac Device Implantation in AL Versus ATTR Amyloidosis"],"prefix":"10.1111","volume":"49","author":[{"given":"Bilal","family":"Hussain","sequence":"first","affiliation":[{"name":"Division of Cardiology University of Cincinnati  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5071-3971","authenticated-orcid":false,"given":"Sanchit","family":"Duhan","sequence":"additional","affiliation":[{"name":"Division of Cardiology Carle Foundation 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