{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T15:59:40Z","timestamp":1790697580920,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T00:00:00Z","timestamp":1772409600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T00:00:00Z","timestamp":1772409600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Early complications after cardiac implantable electronic device (CIED) implantation remain clinically relevant and have been widely examined in large registry studies. Advanced age, comorbidities, device complexity, and antithrombotic therapy are recognized predictors of early complications. This study planned to examine the effect of sex on early (\u2264 30 days) device\u2010related complications and to determine independent predictors of early major adverse cardiac events (MACE).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective, single\u2010center study enrolled 1807 sequential patients (729 women, 1078 men) undergoing pacemaker, implantable cardioverter\u2010defibrillator, or cardiac resynchronization therapy implantation. Early MACE was described as consisting of pocket hematoma, pneumothorax, pericardial effusion\/tamponade, and device\u2010related infection within 30 days. Univariable and multivariable logistic regression analyses were conducted to determine autonomous prognostic factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Early MACE occurred in 26 (3.6%) women and 41 (3.8%) men (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.893). Device type distribution differed significantly by sex, with defibrillators more frequently implanted in men and pacemakers and resynchronization devices in women (all\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001). Sex was not independently related to early MACE (OR 1.28, 95% CI 0.77\u20132.13;\n                      <jats:italic>p<\/jats:italic>\n                      = 0.337). Higher PORT scores (OR 1.06,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.035), higher white blood cell counts (OR 1.09,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.004), lower hemoglobin levels (OR 0.86,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.024), and the presence of heart failure (OR 0.35,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.002) remained independent predictors of early MACE.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Early CIED\u2010related complications were infrequent and occurred at similar rates in women and men. Sex was not an independent predictor of early MACE; instead, overall clinical risk burden and systemic factors were the primary determinants of early adverse outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pace.70194","type":"journal-article","created":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T04:25:17Z","timestamp":1773030317000},"page":"388-394","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Sex Differences in Early Complications After Cardiac Implantable Electronic Device Implantation: Myth or Reality?"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3780-7137","authenticated-orcid":false,"given":"Ali","family":"Evsen","sequence":"first","affiliation":[{"name":"Department of Cardiology Da\u011fkap\u0131 State Hospital  Diyarbak\u0131r Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raif","family":"Kili\u00e7","sequence":"additional","affiliation":[{"name":"Department of Cardiology Mardin Artuklu University Faculty of Medicine  Mardin Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,2]]},"reference":[{"issue":"1","key":"e_1_2_11_2_1","first-page":"58","article-title":"2013 ESC Guidelines on Cardiac Pacing and Cardiac Resynchronization Therapy","volume":"67","author":"Brignole M.","year":"2014","journal-title":"Revista Espa\u00f1ola De Cardiolog\u00eda"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht511"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.976076"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40520-023-02524-6"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2011.12.014"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.12.056"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.119.007545"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.4982"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2015.02.025"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.118.010869"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/openhrt-2014-000198"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.15420\/AER.2015.04.02.129"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.11.029"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199701233360402"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2005.01.006"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12170-011-0186-0"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-156-3-201202070-00007"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.04.033"},{"issue":"3","key":"e_1_2_11_20_1","first-page":"245","article-title":"Complications After Surgical Procedures in Patients With Cardiac Implantable Electronic Devices: Results of a Prospective Registry","volume":"107","author":"Silva K. 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