{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T12:08:57Z","timestamp":1784030937324,"version":"3.55.0"},"reference-count":17,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T00:00:00Z","timestamp":1774569600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T00:00:00Z","timestamp":1774569600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cryoablation is commonly used for pediatric atrioventricular nodal reentrant tachycardia (AVNRT) due to its excellent safety profile and nearly zero risk of permanent atrioventricular (AV) block. However, limited data comparing 6\u2010 and 8\u2010mm cryocatheter tips in large pediatric cohorts are available. This study aims to evaluate and compare the procedural characteristics, acute success, and long\u2010term outcomes of 6\u2010 and 8\u2010mm cryoablation catheters in children undergoing slow pathway modification for AVNRT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We retrospectively reviewed 343 pediatric patients (\u226418 years) who underwent cryoablation for AVNRT between 2016 and 2025. Patients were treated with either a 6\u2010mm (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0182) or an 8\u2010mm (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0161) cryocatheter. Baseline characteristics, electrophysiological parameters, procedural metrics, complications, and recurrence outcomes were analyzed. All procedures used three\u2010dimensional electroanatomical mapping to improve anatomical accuracy and reduce fluoroscopy exposure.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Patients in the 8\u2010mm group were older and heavier and had a higher rate of prior ablation (21.1%\u00a0vs. 6.0%), indicating greater procedural complexity. Procedure duration, total cryotherapy time, and the number of lesions were significantly longer in the 8\u2010mm group. Acute success rates were excellent in both groups (99.5%\u00a0vs. 100%), and there were no cases of permanent AV block, pericardial effusion, or major complications. Over a median follow\u2010up of 69 months in the 6\u2010mm group and 30 months in the 8\u2010mm group, recurrence rates were 15.4% and 10.6%, respectively (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.246), showing a favorable but non\u2010significant trend toward fewer recurrences with the 8\u2010mm catheter.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Both 6\u2010 and 8\u2010mm cryoablation catheters offer highly safe and effective treatment for pediatric AVNRT. Despite being used in more complex cases, the 8\u2010mm catheter achieved comparable acute results and showed a potential long\u2010term benefit, supporting its use in selected patient groups.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pace.70230","type":"journal-article","created":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T12:10:09Z","timestamp":1774613409000},"page":"815-821","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Long\u2010Term Outcomes of 6\u2010mm Versus 8\u2010mm Cryoablation for Pediatric AVNRT: A Large Single\u2010Center Study"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0529-2391","authenticated-orcid":false,"given":"Cem","family":"Karadeniz","sequence":"first","affiliation":[{"name":"Department of Pediatric Cardiology Pediatric Arrhythmia &amp; Electrophysiology Unit Izmir Katip Celebi University  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammed Akif","family":"Atlan","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Izmir City Hospital  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sedef","family":"Oksuz","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Izmir City Hospital  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaan","family":"Y\u0131ld\u0131z","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Izmir City Hospital  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gozde Gursoy","family":"Cirkinoglu","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Izmir City Hospital  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hakan","family":"Dedecengiz","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Izmir City Hospital  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tolga","family":"Bacak","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Izmir City Hospital  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berkay","family":"Alimoglu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Izmir City Hospital  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Engin","family":"Gerceker","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Izmir City Hospital  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferhan","family":"Elmal\u0131","sequence":"additional","affiliation":[{"name":"Department of Biostatistics Izmir Katip Celebi University  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazmi","family":"Narin","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Izmir Katip Celebi University  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,27]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euaa325"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540\u20108167.2004.03645.x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.970350"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12339"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00246\u2010022\u201002887\u2010z"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2006.01.026"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540\u20108159.2011.03244.x"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540\u20108167.2008.01224.x"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.13367"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00246\u2010017\u20101648\u2010z"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840\u2010020\u201000868\u2010x"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00246\u2010012\u20100273\u20100"},{"key":"e_1_2_10_14_1","first-page":"337","article-title":"Transcatheter Cryoablation Procedures Without Fluoroscopy in Pediatric Patients With Atrioventricular Nodal Reentrant Tachycardia: A Single\u2010Center Experience","volume":"34","author":"Balli S.","year":"2018","journal-title":"Acta Cardiologica Sinica"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2025.1527768"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.116.004264"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euw145"},{"key":"e_1_2_10_18_1","first-page":"122","article-title":"Cryoablation Versus Radiofrequency Ablation for Atrioventricular Nodal Reentrant Tachycardia in Children: Long\u2010Term Results","volume":"51","author":"Papagiannis J.","year":"2010","journal-title":"Hellenic Journal of Cardiology"}],"container-title":["Pacing and Clinical 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