{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T15:54:56Z","timestamp":1792425296012,"version":"4.5.0"},"reference-count":38,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T00:00:00Z","timestamp":1776124800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T00:00:00Z","timestamp":1776124800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Leadless pacemakers (LPs) are developed to avoid pocket\u2010 and lead\u2010related complications of transvenous pacing systems, but direct comparative data between two single chamber LP, namely Micra VR and Aveir VR are scarce.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic review and meta\u2010analysis of studies directly comparing Micra VR and Aveir VR was performed. PubMed, Embase, and Scopus were searched through November 2025. Eligible studies reported electrical performance, procedural metrics, or periprocedural complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Four observational studies, including 757 patients (363 Aveir, 394 Micra), met the inclusion criteria, with follow\u2010up of 1\u20136 months. At implantation, Aveir showed slightly higher pacing thresholds (mean difference (MD) 0.18\u00a0V; 95% CI 0.09\u20130.26), while impedance and R\u2010wave amplitude were similar. In follow\u2010up, pacing thresholds showed no significant difference between devices, whereas Micra demonstrated higher R\u2010wave amplitudes (MD \u22121.18\u00a0mV; 95% CI \u22122.29 to \u22120.07). Fluoroscopy time was longer with Aveir (MD 2.89\u00a0min; 95% CI 0.69\u20135.08), but total procedure duration did not differ significantly. Rates of device dislodgement, pericardial effusion\/tamponade, and overall periprocedural complications were low and not statistically different between the two systems.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Micra VR and Aveir VR demonstrate generally comparable short\u2010term electrical performance, procedural efficacy, and safety. Minor differences in thresholds, sensing, and fluoroscopy time are likely indicative of design and workflow characteristics. Larger, well\u2010controlled randomized studies with extended follow\u2010up periods are necessary to establish long\u2010term performance.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pace.70253","type":"journal-article","created":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T06:09:35Z","timestamp":1776233375000},"page":"867-875","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Comparative Performance, Procedural Characteristics and Safety of Micra Versus Aveir Leadless Pacemakers: Systematic Review"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2802-4613","authenticated-orcid":false,"given":"Hamidreza","family":"Soleimani","sequence":"first","affiliation":[{"name":"Department of Cardiology, School of Medicine Imam Khomeini Hospital Complex, Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iman","family":"Razeghian","sequence":"additional","affiliation":[{"name":"School of Medicine Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-3386-7697","authenticated-orcid":false,"given":"Parham","family":"Dastjerdi","sequence":"additional","affiliation":[{"name":"Tehran Heart Center, Cardiovascular Diseases Research Institute Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Negin Sadat Hosseini","family":"Mohammadi","sequence":"additional","affiliation":[{"name":"Tehran Heart Center, Cardiovascular Diseases Research Institute Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hedieh","family":"Shayesteh","sequence":"additional","affiliation":[{"name":"Tehran Heart Center, Cardiovascular Diseases Research Institute Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cyrus","family":"Hadadi","sequence":"additional","affiliation":[{"name":"MedStar Heart and Vascular Institute  Washington, DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masoud","family":"Eslami","sequence":"additional","affiliation":[{"name":"Department of Cardiology, School of Medicine Imam Khomeini Hospital Complex, Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2131-0409","authenticated-orcid":false,"given":"Reza","family":"Mollazadeh","sequence":"additional","affiliation":[{"name":"Department of Cardiology, School of Medicine Imam Khomeini Hospital Complex, Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,14]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht511"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2019.11.005"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.006987"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehv214"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2021.11.002"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1511643"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2022.07.021"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2017.05.017"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.14776"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehab767"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i4919"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-75936-4"},{"issue":"394","key":"e_1_2_11_15_1","first-page":"165","article-title":"RStudio: Integrated Development Environment for R","volume":"770","author":"Allaire J. 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