{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T03:51:10Z","timestamp":1791258670375,"version":"4.1.0"},"reference-count":19,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T00:00:00Z","timestamp":1778976000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T00:00:00Z","timestamp":1778976000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82400343"],"award-info":[{"award-number":["82400343"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pacing Clinical Electrophis"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The safety and efficacy profile of the combined \u201cone\u2010stop\u201d catheter ablation (CA) and left atrial appendage occlusion (LAAO) procedure in atrial fibrillation (AF) patients with a prior history of cerebral infarction requires further validation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In this retrospective, single\u2010center study, 242 consecutive AF patients undergoing the one\u2010stop procedure were categorized into Stroke (\n                      <jats:italic>n<\/jats:italic>\n                      = 103) and Non\u2010Stroke (\n                      <jats:italic>n<\/jats:italic>\n                      = 139) groups. A 1:1 propensity score matching (PSM) was performed, yielding 57 balanced pairs. The primary efficacy endpoint was procedural success. Key safety endpoints included post\u2010procedural residual shunt assessed at 45 days, device\u2010related thrombosis (DRT), and stroke recurrence.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After PSM, baseline characteristics were well\u2010balanced. Procedural success (91.2%\u00a0vs. 87.7%,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.484) and freedom from AF recurrence (88.6%\u00a0vs. 89.3%,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.979) were comparable between Stroke and Non\u2010Stroke groups. However, the incidence of residual shunt was significantly higher in the Stroke group (5.3%\u00a0vs. 0%,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.028). No significant differences were observed in DRT or stroke recurrence rates. Notably, a significant interaction was found between prior stroke and LAAO device type on residual shunt risk (\n                      <jats:italic>p<\/jats:italic>\n                      \u2010for\u2010interaction = 0.045), indicating the risk varied substantially depending on the occluder used.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A history of prior stroke does not impair the procedural success or mid\u2010term rhythm control of the one\u2010stop CA+LAAO strategy. However, it is associated with an increased risk of residual shunt, a relationship significantly modified by the type of occluder device. These findings highlight the potential need for individualized device selection in stroke survivors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pace.70254","type":"journal-article","created":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T13:19:26Z","timestamp":1779023966000},"page":"1622-1629","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prior Stroke Increases Residual Shunt Risk After Combined Ablation and LAAO: A Device\u2010Specific Interaction"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-6533-4342","authenticated-orcid":false,"given":"Haoqing","family":"Ren","sequence":"first","affiliation":[{"name":"Jiangxi Medical College Nanchang University  Nanchang China"},{"name":"Department of Cardiology Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College  Nanchang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hengli","family":"Lai","sequence":"additional","affiliation":[{"name":"Department of Cardiology Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College  Nanchang China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,17]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.120.316340"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.15759"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/23969873221099478"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.27.10.1760"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.25489"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1412981"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.121.034777"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-19-0602"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2408308"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.119.007612"},{"issue":"2","key":"e_1_2_14_12_1","first-page":"225","article-title":"Combining Left Atrial Appendage Closure and Catheter Ablation for Atrial Fibrillation: 2\u2010Year Outcomes From a Multinational Registry","volume":"22","author":"Phillips K. P.","year":"2020","journal-title":"Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology: Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2022.05.003"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euaa365"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2025.112981"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.04.032"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2022.5449"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.114.005540"},{"key":"e_1_2_14_19_1","doi-asserted-by":"publisher","DOI":"10.7326\/M16-2607"},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehv730"}],"container-title":["Pacing and Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.70254","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pace.70254","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pace.70254","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T03:10:22Z","timestamp":1791256222000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pace.70254"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,17]]},"references-count":19,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1111\/pace.70254"],"URL":"https:\/\/doi.org\/10.1111\/pace.70254","archive":["Portico"],"relation":{},"ISSN":["0147-8389","1540-8159"],"issn-type":[{"value":"0147-8389","type":"print"},{"value":"1540-8159","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,17]]},"assertion":[{"value":"2026-01-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}